Basic information
- Name:
3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester,hydrochloride (1:1)
- Superlist Name:
- Lercanidipine hydrochloride
- CAS No.:
132866-11-6
- Molecular Structure:
![Molecular Structure of 132866-11-6 (3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester,hydrochloride (1:1))](http://www.lookchem.com/300w/2010/0618/132866-11-6.jpg)
- Formula:
- C36H42ClN3O6
- Molecular Weight:
- 648.19
- Synonyms:
- 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester,monohydrochloride (9CI);Cardiovasc;Carmen;Corifeo;Lercadip;Lercan;Lercapin;Lercaton;Lerkamen;Lerzam;R 75;Rec15/2375;Renovia;Vasodip;Zandip;Zanicor;
- Melting Point:
- 175-177 °C
- Boiling Point:
- 712.5 °C at 760 mmHg
- Flash Point:
- 384.7 °C
- Appearance:
- pale-yellow powder
- Hazard Symbols:
T- Risk Codes:
- 25
- Safety Description:
- 36/37-45 Details
- Transport Information:
- UN 2811
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Chemistry
IUPAC Name: 3-O-[1-[3,3-Diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 5-O-methyl2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylatehydrochloride
Following is the structure of 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester,hydrochloride (1:1) (CAS NO.132866-11-6):

Empirical Formula: C36H42ClN3O6
Molecular Weight: 648.1882
Flash Point: 384.7 °C
Storage temp.: 2-8 °C
Melting point: 175-177 °C
Enthalpy of Vaporization: 104.17 kJ/mol
Boiling Point: 712.5 °C at 760 mmHg
Vapour Pressure: 3.77E-20 mmHg at 25 °C
Appearance 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester,hydrochloride (1:1) (CAS NO.132866-11-6): Pale-Yellow Powder
Product Categories 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester,hydrochloride (1:1) (CAS NO.132866-11-6): Miscellaneous Natural Products; Dihydropyridine Class Chemicals; Intermediates & Fine Chemicals; Pharmaceuticals; Calcium Channel Modulators; Inhibitors and Activators; Voltage-gated Ion Channels
Canonical SMILES: CC1=C(C(C(=C(N1)C)C(=O)OC(C)(C)CN(C)CCC(C2=CC=CC=C2)C3=CC=CC=C3)C4=CC(=CC=C4)[N+](=O)[O-])C(=O)OC.Cl
InChI: InChI=1S/C36H41N3O6.ClH/c1-24-31(34(40)44-6)33(28-18-13-19-29(22-28)39(42)43)32(25(2)37-24)35(41)45-36(3,4)23-38(5)21-20-30(26-14-9-7-10-15-26)27-16-11-8-12-17-27;/h7-19,22,30,33,37H,20-21,23H2,1-6H3;1H
InChIKey: WMFYOYKPJLRMJI-UHFFFAOYSA-N
Uses
3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester,hydrochloride (1:1) (CAS NO.132866-11-6) can be used as a dihydropyridine calcium channel blocker.
Safety Profile
Hazard Codes:
T
Risk Statements: 25
S25:Avoid contact with eyes.
Safety Statements: 36/37-45
S36/37:Wear suitable protective clothing and gloves.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2811
Specification
3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester,hydrochloride (1:1) , its cas register number 132866-11-6. It also can be called Lercanidipine hydrochloride ; and 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester hydrochloride ; Cardiovasc ; Carmen ; Corifeo ; Lercadip ; Lercan ; Lercanidipine HCl ; Lercanidipine hydrochloride ; Lercapin ; Lercaton ; Lerkamen ; Lerzam ; Vasodip ; Zandip ; and Zanicor . Its classification code are Antihypertensive compound and Calcium channel blockers.

