Table of contents:
Molecular Formula: C6H6N2O2
Molar mass: 138.12 g/mol
EINECS: 202-729-1
Density: 1.333 g/cm3
Flash Point: 139.5 °C
Index of Refraction: 1.634
Boiling Point: 307 °C at 760 mmHg
Vapour Pressure: 0.000745 mmHg at 25°C
Melting point: 111-114 °C(lit.)
Water solubility: 1.25 g/L
Appearance: Ochre-yellow to orange crystalline powder
Product categories: Intermediates of Dyes and Pigments;Aromatics Chemical Class;Nitro Compounds;Anilines, Aromatic Amines and Nitro Compounds;Functional Materials;Organic Nonlinear Optical Materials;Alpha Sort;Analytical Standards;Aromatics Volatiles/ Semivolatiles;NA - NI Analytical Standards;N-OAlphabeticPhotonic and Optical Materials;NLO Chromophores and Intermediates;Non-Linear Optical (NLO) Materials
Structure of 3-Nitroaniline (99-09-2):
XLogP3-AA: 1.4
H-Bond Donor: 1
H-Bond Acceptor: 3
IUPAC Name: 3-nitroaniline
Canonical SMILES: C1=CC(=CC(=C1)[N+](=O)[O-])N
InChI: InChI=1S/C6H6N2O2/c7-5-2-1-3-6(4-5)8(9)10/h1-4H,7H2
InChIKey: XJCVRTZCHMZPBD-UHFFFAOYSA-N
3-Nitroaniline (99-09-2) is used as a chemical intermediate for azo coupling component 17 and the dyes disperse yellow 5 and acid blue 29. The chemical is changed to other substances during the dyeing process.
| 1. |
mmo-sat 15 mmol/L |
AEMIDF Applied and Environmental Microbiology. 44 (1982),801. | ||
| 2. |
mma-sat 10 µmol/plate |
MUREAV Mutation Research. 58 (1978),11. | ||
| 3. |
orl-rat LD50:535 mg/kg |
AMRL** Aerospace Medical Research Laboratory Report. (Aerospace Technical Div., Air Force Systems Command, Wright-Patterson Air Force Base, OH 45433) TR-72-62 ,1972. | ||
| 4. |
orl-mus LD50:308 mg/kg |
AMRL** Aerospace Medical Research Laboratory Report. (Aerospace Technical Div., Air Force Systems Command, Wright-Patterson Air Force Base, OH 45433) TR-72-62 ,1972. | ||
| 5. |
ipr-dog LDLo:70 mg/kg |
JIDHAN Journal of Industrial Hygiene. 2 (1920),247. | ||
| 6. |
orl-gpg LD50:450 mg/kg |
VKMGA7 Voprosy Kommunalnoi Gigieny. Problems of Communal Hygiene. 6 (1966),89. | ||
| 7. |
orl-qal LD50:562 mg/kg |
AECTCV Archives of Environmental Contamination and Toxicology. 12 (1983),355. |
Carcinogenicity of 3-Nitroaniline (99-09-2) hasn't been listed as a carcinogen by NTP, IARC,ACGIH, or CA Prop 65. You can see actual entry in RTECS for complete information.
Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.
Poison by ingestion and intraperitoneal routes. Mutation data reported. Absorbed through the skin and by inhalation of the dust. Acute exposure may cause methemoglobinemia cyanosis. Chronic exposure may cause liver damage. Flammable liquid. Decomposes exothermically at 247°C. Possibly explosive reaction with ethylene oxide at 130°C. When heated to decomposition it emits toxic fumes of NOx. See also o-NITROANILINE, p-NITROANILINE, and ANILINE DYES.
Hazard Codes: T.gif){kind=small}
Risk Statements:
23: Toxic by inhalation
24: Toxic in contact with skin
25: Toxic if swallowed
33: Danger of cumulative effects
52: Harmful to aquatic organisms
53: May cause long-term adverse effects in the aquatic environment
Safety Statements:
28A After contact with skin, wash immediately with plenty of water.
36: Wear suitable protective clothing
37: Wear suitable gloves
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
61: Avoid release to the environment. Refer to special instructions safety data sheet
DOT Classification: 3; Label: Flammable Liquid
3-Nitroaniline (99-09-2), also can be called 3-Nitrophenylamine ; m-Nitrophenylamine ; meta-Nitroaniline ; benzenamine, 3-nitro- , is non-volatile stable solid commonly used as a raw material for dyes and Pigments.It is an aniline carrying a nitro functional group in position 3.It is hazardous,so the first aid measures and others should be known.Such as: When on the skin: first,should flush skin with plenty of water immediatelyfor at least 15 minutes while removing contaminated clothing. Secondly,Get shoesmedical aid . Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.Then get medical aid soon.While ,it's Inhaled: Remove from exposure and move to fresh air immediately.Give artificial respiration while not breathing. When breathing is difficult, give oxygen. And as soon as to get medical aid. Then you have the ingesting of the product : Wash mouth out with water,and get medical aid immediately.Notes to physician: Treat supportively and symptomatically.
In addition, 3-Nitroaniline (99-09-2) can be stable under normal temperature and pressure conditions.It is not compatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides, chloroformates,and you must not take it with incompatible materials.And also prevent it to broken down into hazardous decomposition products: oxides of nitrogen, carbon dioxide, carbon monoxide.
