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3-Pyridinepropanol

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Name

3-Pyridinepropanol

EINECS 220-675-7
CAS No. 2859-67-8 Density 1.059 g/cm3
PSA 33.12000 LogP 1.00650
Solubility N/A Melting Point N/A
Formula C8H11NO Boiling Point 283.999 °C at 760 mmHg
Molecular Weight 137.181 Flash Point 116.378 °C
Transport Information N/A Appearance N/A
Safety 26-37/39 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 2859-67-8 (3-Pyridinepropanol) Hazard Symbols IrritantXi
Synonyms

3-(3-Hydroxypropyl)pyridine;3-(3-Pyridinyl)-1-propanol;3-(3-Pyridyl)-1-propanol;3-(3-Pyridyl)propanol;3-(Pyridin-3-yl)propanol;3-(b-Pyridyl)propanol;NSC 66564;

Article Data 10

3-Pyridinepropanol Specification

The 3-Pyridinepropanol, its cas register number is 2859-67-8. It also can be called as 3-(3-Pyridyl)-1-propanol and the IUPAC name about this chemical is 3-Pyridin-3-ylpropan-1-ol. It belongs to the Heterocyclic Compounds.

Physical properties about 3-Pyridinepropanol are: (1)#H bond acceptors: 2; (2)#H bond donors: 1; (3)#Freely Rotating Bonds: 4; (4)Polar Surface Area: 22.12Å2; (5)Index of Refraction: 1.53; (6)Molar Refractivity: 40.06 cm3; (7)Molar Volume: 129.4 cm3; (8)Polarizability: 15.88x10-24cm3; (9)Surface Tension: 44.5 dyne/cm; (10)Enthalpy of Vaporization: 55.23 kJ/mol; (11)Vapour Pressure: 0.00144 mmHg at 25°C

Uses of 3-Pyridinepropanol: it can react with 1-fluoro-4-nitro-benzene to give 3-[3-(4-nitro-phenoxy)-propyl]-pyridine.

This reaction needs reagent dimethylformamide and NaH at temperature of 0 ℃ . The reaction time is 1 hours. The yield is 75.7 % .

When you are using this chemical, you should be very cautious. Being a kind of irritant chemical, it is irritating to eyes, respiratory system and skin. When you are contacting with it, wear suitable gloves and eye/face protection. And if in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C1=CC(=CN=C1)CCCO
(2)InChI: InChI=1S/C8H11NO/c10-6-2-4-8-3-1-5-9-7-8/h1,3,5,7,10H,2,4,6H2
(3)InChIKey: ZUGAIMFLQLPTKB-UHFFFAOYSA-N

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 180mg/kg (180mg/kg)   U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#01584,

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