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4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid

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4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid

EINECS 229-560-6
CAS No. 145069-56-3 Density 1.277 g/cm3
PSA 103.32000 LogP 6.18620
Solubility N/A Melting Point ~180 °C (dec.)
Formula C32H29NO7 Boiling Point 776.3 °C at 760 mmHg
Molecular Weight 539.585 Flash Point 423.3 °C
Transport Information N/A Appearance N/A
Safety 22-24/25-37/39-26 Risk Codes 36/38
Molecular Structure Molecular Structure of 145069-56-3 (4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid) Hazard Symbols IrritantXi
Synonyms

P-((R,S)-alpha-[1-(9h-fluoren-9-yl)-methoxyformamido]-2,4-dimethoxybenzyl)-phenoxyacetic acid;N-alpha-(9-fluorenylmethoxycarbonyl)-2,4-dimethoxy-4'-(carboxymethyloxy)-benzhydrylamine;4-(R,S)-a-[1-(9h-fluoren-9-yl)-methoxy-formamido]-2,4-dimethoxybenzyl-phenoxyacetic-acid;Rink Amide Linker;

Article Data 1

4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid Chemical Properties

Molecular Structure of Rink Amide Linker (CAS NO.145069-56-3):

Molecualr Formula: C32H29NO7
Molecular Weight: 539.58
H bond acceptors: 8
H bond donors: 2
Freely Rotating Bonds: 11
Polar Surface Area: 83.53 Å2
Index of Refraction: 1.619
Molar Refractivity: 148.24 cm3
Molar Volume: 422.3 cm3
Surface Tension: 53 dyne/cm
Density: 1.277 g/cm3
Flash Point: 423.3 °C
Enthalpy of Vaporization: 118.52 kJ/mol
Boiling Point: 776.3 °C at 760 mmHg
Vapour Pressure: 2.31E-25 mmHg at 25°C
Melting point:  ~180 °C (dec.)
Storage temp:  2-8°C
Product Categories: Pharmaceutical Raw Materials; Protected amino acid & peptides; Linkers for Solid Phase Synthesis; Linkers for solid phase synthesis

4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid Safety Profile

Hazard Codes: IrritantXi
Risk Statements: 36/38 
R36/38:Irritating to eyes and skin.
Safety Statements:  22-24/25-37/39-26 
S22:Do not breathe dust. 
S24/25:Avoid contact with skin and eyes. 
S37/39:Wear suitable gloves and eye/face protection. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 3

4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid Specification

 Rink Amide Linker , with CAS number of 145069-56-3, can be called Rink amide reagent;rink amide linker ; N-fmoc-(2,4-dimethoxyphenyl)aminomethyl phenoxy acetic acid ; P-[(r,s)-a-[1-(9h-fluoren-9-yl)-methoxyformamido]-2,4-dimethoxybenzyl]-phenoxyacetic acid ; P-((R,S)-alpha-[1-(9h-fluoren-9-yl)-methoxyformamido]-2,4-dimethoxybenzyl)-phenoxyacetic acid ; P-((R,S)-alpha-[1-(9h-flouren-9-yl)-methoxyformamido]-2,4-dimethoxybenzyl)-phenoxyacetic acid ; N-alpha-(9-fluorenylmethoxycarbonyl)-2,4-dimethoxy-4'-(carboxymethyloxy)-benzhydrylamine ; 4-(R,S)-a-[1-(9h-fluoren-9-yl)-methoxy-formamido]-2,4-dimethoxybenzyl-phenoxyacetic-acid . Rink Amide Linker (CAS NO.145069-56-3) is commonly used as link agent which is commonly applicated for organic synthesis.

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