Related Products
- 104048-92-22-Hydroxy-4-(trifluoromethyl)pyrimidine
- 10405-02-4Trospium chloride
- 1040502-51-93-(methylthio)-1H-indazole
- 104051-15-2Vasoactive intestinaloctacosapeptide (swine), 2-D-phenylalanine- (9CI)
- 104051-62-9ethyl 1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylate
- 104054-27-51H-Imidazole,5-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-
- 104055-46-1D-Serine, ethyl ester,hydrochloride (1:1)
- 104055-76-7Quinovic acid 3-O-alpha-L-rhamnopyranoside
- 104055-79-04H,8H-Benzo[1,2-b:3,4-b']dipyran-4-one, 2,3,9,10-tetrahydro-5-hydroxy-8,8-dimethyl-2-phenyl-, (S)-
- 10405-85-3trans-4-Nonene
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
4'-Nitroacetanilide |
EINECS | 203-169-0 |
| CAS No. | 104-04-1 | Density | 1.341 g/cm3 |
| PSA | 74.92000 | LogP | 2.14940 |
| Solubility | 2.2g/L(room temperature) | Melting Point |
213-215 °C(lit.) |
| Formula | C8H8N2O3 | Boiling Point | 408.89 °C at 760 mmHg |
| Molecular Weight | 180.163 | Flash Point | 201.09 °C |
| Transport Information | N/A | Appearance | solid |
| Safety | 26-36 | Risk Codes | 36/37/38 |
| Molecular Structure |
|
Hazard Symbols |
 Xi
|
| Synonyms |
N-Acetyl-4-nitroaniline;N-Acetyl-4-nitrobenzenamine;N-Acetyl-p-nitroaniline;NSC 1315;p-Acetamidonitrobenzene;p-Nitroacetanilide;Acetanilide,4'-nitro- (6CI,8CI);Acetanilide, p-nitro- (3CI);1-Nitro-4-acetylaminobenzene;4-(Acetylamino)nitrobenzene;N-(4-Nitrophenyl)acetamide;N-(p-Nitrophenyl)acetamide; |
Article Data | 300 |
4'-Nitroacetanilide Synthetic route
Conditions
| Conditions | Yield |
|---|---|
| In dichloromethane at 20℃; for 16h; | 99.5% |
| With pyridine In dichloromethane at 0 - 20℃; for 1h; | 97% |
| In water at 80℃; for 0.0833333h; Microwave irradiation; Green chemistry; chemoselective reaction; | 96% |
Conditions
| Conditions | Yield |
|---|---|
| With sodium nitrate; sulfuric acid at 0 - 5℃; for 3h; | 99% |
| With ammonium molybdate; water; nitric acid In chloroform for 6h; Nitration; Heating; | 99% |
| With nitric acid; cetyltrimethylammonim bromide In acetonitrile at 24.84℃; for 2h; Micellar solution; regioselective reaction; | 85% |
- 10342-64-0
p-nitroacetophenone oxime
- 104-04-1
N-(4-Nitrophenyl)acetamide
Conditions
| Conditions | Yield |
|---|---|
| With chlorosulfonic acid In toluene at 90℃; for 0.5h; Beckmann rearrangement; | 99% |
| With trifluoromethylsulfonic anhydride In dichloromethane at 20℃; for 2h; Beckmann Rearrangement; Inert atmosphere; | 94% |
| With 2-chloro-1-methyl-pyridinium iodide; triethylamine In acetonitrile at 20℃; Beckmann Rearrangement; | 93% |
Conditions
| Conditions | Yield |
|---|---|
| With aluminum oxide at 25℃; for 0.666667h; | 98% |
| With lanthanum(III) nitrate at 20℃; for 0.25h; | 98% |
| In ethyl acetate at 20℃; for 20h; Inert atmosphere; | 98% |
- 10319-77-4
N-(4-nitrophenyl)ethanethioamide
- 104-04-1
N-(4-Nitrophenyl)acetamide
Conditions
| Conditions | Yield |
|---|---|
| With bismuth(III) nitrate In acetonitrile for 0.166667h; Heating; | 98% |
| With acidified wet silica gel; tetrabutylammonium periodite at 20℃; for 0.0333333h; Neat (no solvent); | 97% |
| at 20℃; for 0.0833333h; Neat (no solvent); | 96% |
Conditions
| Conditions | Yield |
|---|---|
| Stage #1: 4-nitro-aniline; diethyl malonate at 100 - 130℃; Stage #2: With caesium carbonate In 1,4-dioxane at 100℃; | 98% |
Conditions
| Conditions | Yield |
|---|---|
| With manganese(III) acetate; ammonium thiocyanate at 25℃; for 2h; | 95% |
| With Starbon-400-SO3H at 130℃; for 0.0333333h; Microwave irradiation; chemoselective reaction; | 92% |
| With palladium (II) nanoparticles supported on Schiff-base modified clinoptilolite nanocatalyst In neat (no solvent) at 20℃; for 0.25h; Green chemistry; chemoselective reaction; | 92% |
- 59862-56-5
4-nitroacetophenone oxime
- 104-04-1
N-(4-Nitrophenyl)acetamide
Conditions
| Conditions | Yield |
|---|---|
| With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide In tetrahydrofuran; ethyl acetate at 70℃; for 3h; Beckmann rearrangement; Inert atmosphere; | 94% |
Conditions
| Conditions | Yield |
|---|---|
| With O-benzenesulfonyl-acetohydroxamic acid ethyl ester; toluene-4-sulfonic acid In water; acetonitrile at 23℃; for 24h; Inert atmosphere; | 92% |
| With sodium azide; sulfuric acid; silica gel at 60℃; for 0.75h; Schmidt reaction; | 90% |
| With formic acid; hydroxylamine hydrochloride; silica gel at 80℃; for 4h; Beckmann Rearrangement; | 90% |
Conditions
| Conditions | Yield |
|---|---|
| With 3-chloro-benzenecarboperoxoic acid In 1,2-dichloro-ethane for 10h; Reflux; | 92% |
| With 1,9-diperoxynonanedioic acid In acetonitrile at 50℃; for 0.5h; | 86% |
| With water; fluorine In chloroform; acetonitrile at -15℃; for 0.0333333h; | 80% |
| With sodium perborate In acetic acid at 50 - 60℃; for 2h; | 55% |
4'-Nitroacetanilide Chemical Properties
MF: C8H8N2O3
MW: 180.16
EINECS: 203-169-0
mp: 213-215 °C(lit.)
storage temp: 2-8°C
Merck: 14,6581
BRN: 2211962
CAS DataBase Reference: 104-04-1(CAS DataBase Reference)
Synonyms:P-NITROACETANILIDE;N-ACETYL-4-NITROANILINE;LABOTEST-BB LT00455738;4'-NITROACETANILIDE;4-NITROACETANILIDE;ACETIC ACID 4-NITROANILIDE;1-Nitro-4-acetylaminobenzene;Acetamide, N-(4-nitrophenyl)-
The structure of p-NITROACETANILIDE(104-04-1) is:
4'-Nitroacetanilide Toxicity Data With Reference
1、RTECS#: CAS# 104-04-1: AE5075000
2、LD50/LC50: RTECS: Not available.
3、Carcinogenicity: 4'-Nitroacetanilide - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.
4、Other: See actual entry in RTECS for complete information. The toxicological properties have not been fully investigated.
2、LD50/LC50: RTECS: Not available.
3、Carcinogenicity: 4'-Nitroacetanilide - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.
4、Other: See actual entry in RTECS for complete information. The toxicological properties have not been fully investigated.
4'-Nitroacetanilide Consensus Reports
p-NITROACETANILIDE(104-04-1) is reported in EPA TSCA Inventory.
4'-Nitroacetanilide Safety Profile
Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: AE5075000
Moderately toxic by intraperitoneal route. Reaction with sulfuric acid is vigorous with much gas evolution. When heated to decomposition it emits toxic fumes of NOx.
4'-Nitroacetanilide Specification
1、Fire Fighting Measures of p-NITROACETANILIDE(104-04-1)
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.
2、Handling and Storage of p-NITROACETANILIDE(104-04-1)
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Storage: Store in a cool, dry place. Store in a tightly closed container.
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.
2、Handling and Storage of p-NITROACETANILIDE(104-04-1)
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Storage: Store in a cool, dry place. Store in a tightly closed container.
Post a RFQ
1
What can I do for you?
Get Best Price
Get Best Price for 104-04-1
4'-NITROACETANILIDE
