Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

4-Amino-3-chloro-2,5,6-trifluoropyridine

Related Products

Hot Products

Name

4-Amino-3-chloro-2,5,6-trifluoropyridine

EINECS N/A
CAS No. 2693-57-4 Density 1.666 g/cm3
PSA 38.91000 LogP 2.31570
Solubility N/A Melting Point 120-121ºC
Formula C5H2ClF3N2 Boiling Point 243.8 °C at 760 mmHg
Molecular Weight 182.53 Flash Point 101.3 °C
Transport Information N/A Appearance N/A
Safety 26-36/37/39 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 2693-57-4 (4-AMINO-3-CHLORO-2,5,6-TRIFLUOROPYRIDINE) Hazard Symbols IrritantXi
Synonyms

Pyridine,4-amino-3-chloro-2,5,6-trifluoro- (8CI);(3-Chloro-2,5,6-trifluoropyridin-4-yl)amine;2,3,6-Trifluoro-5-chloro-4-aminopyridine;3-Chloro-2,5,6-trifluoro-4-pyridinamine;3-Chloro-2,5,6-trifluoropyrid-4-ylamine;3-Chloro-4-aminoperfluoropyridine;4-Amino-3-chloro-2,5,6-trifluoropyridine;4-Amino-3-chlorotrifluoropyridine;

Article Data 12

4-Amino-3-chloro-2,5,6-trifluoropyridine Specification

The 4-Amino-3-chloro-2,5,6-trifluoropyridine, with the cas registry number 2693-57-4, has the systematic name of 3-chloro-2,5,6-trifluoropyridin-4-amine. It belongs to the following product categories: C5; Heterocyclic Building Blocks; Halogenated Heterocycles; Heterocyclic Building Blocks; Pyridines. And the molecular formula of the chemical is C5H2ClF3N2.

The characteristics of this chemical are as followings: (1)ACD/LogP: 2.46; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.46; (4)ACD/LogD (pH 7.4): 2.46; (5)ACD/BCF (pH 5.5): 43.72; (6)ACD/BCF (pH 7.4): 43.72; (7)ACD/KOC (pH 5.5): 520.03; (8)ACD/KOC (pH 7.4): 520.03; (9)#H bond acceptors: 2; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 16.13 Å2; (13)Index of Refraction: 1.523; (14)Molar Refractivity: 33.45 cm3; (15)Molar Volume: 109.5 cm3; (16)Polarizability: 13.26×10-24cm3; (17)Surface Tension: 45.5 dyne/cm; (18)Density: 1.666 g/cm3; (19)Flash Point: 101.3 °C; (20)Enthalpy of Vaporization: 48.09 kJ/mol; (21)Boiling Point: 243.8 °C at 760 mmHg; (22)Vapour Pressure: 0.0314 mmHg at 25°C.

Preparation of 4-Amino-3-chloro-2,5,6-trifluoropyridine: This chemical can be prepared by 3-chloro-2,4,5,6-tetrafluoro-pyridine. The reaction will need reagent aq. NH4OH. The reaction time is 5 hours with temperature of 20°C, and the yield is about 99%. 

Uses of 4-Amino-3-chloro-2,5,6-trifluoropyridine: It can be used to produce 2,3,6-trifluoro-pyridin-4-ylamine. This reaction will need reagent Et3N and H2, catalyst 10% Pd/C, and the menstruum ethanol. The reaction time is 18 hours with pressure of 2585.74Pa, and the yield is about 96%.

You should be cautious while dealing with this chemical. It irritates to eyes, respiratory system and skin. Therefore, you had better take the following instructions: Wear suitable protective clothing, gloves and eye/face protection, and if in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.

Addtionally, the following datas could be converted into the molecular structure:
(1)SMILES: Clc1c(N)c(F)c(F)nc1F
(2)InChI: InChI=1/C5H2ClF3N2/c6-1-3(10)2(7)5(9)11-4(1)8/h(H2,10,11)
(3)InChIKey: IJGMBUFHHBUVNG-UHFFFAOYAP

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 2693-57-4