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Name	4-Chloro-2-Nitrobenzoic Acid	EINECS	228-483-5
CAS No.	6280-88-2	Density	1.602 g/cm³
PSA	83.12000	LogP	2.46960
Solubility	water: 0.53 g/100 mL (15 °C)	Melting Point	141-143 °C(lit.)
Formula	C₇H₄ClNO₄	Boiling Point	357 °C at 760 mmHg
Molecular Weight	201.566	Flash Point	169.7 °C
Transport Information	UN 2811 6.1/PG 3	Appearance	light yellow to light yellow-green crystalline
Safety	26-36-24/25	Risk Codes	36/37/38
Molecular Structure		Hazard Symbols	Xi
Synonyms	2-Nitro-4-chlorobenzoicacid;NSC 6158;	Article Data	18

4-Chloro-2-Nitrobenzoic Acid Synthetic route

: 34662-32-3
4-chloro-2-nitrobenzonitrile

: 6280-88-2
4-chloro-2-nitro-benzoic acid

Conditions

Conditions	Yield
With sulfuric acid
With sulfuric acid
With sulfuric acid
Multi-step reaction with 2 steps 1: sulfuric acid 2: sulfuric acid View Scheme

: 89-59-8
4-chloro-2-nitrotoluene

: 6280-88-2
4-chloro-2-nitro-benzoic acid

Conditions

Conditions	Yield
With nitric acid at 200℃;
With pyridine; potassium permanganate; water
With potassium permanganate

: 2001-16-3
4-chloro-1-ethyl-2-nitrobenzene

: 6280-88-2
4-chloro-2-nitro-benzoic acid

Conditions

Conditions	Yield
With potassium permanganate

: 41994-91-6
4-chloro-2-nitrobenzoic amide

: 6280-88-2
4-chloro-2-nitro-benzoic acid

Conditions

Conditions	Yield
With sulfuric acid

: 89-59-8
4-chloro-2-nitrotoluene

: 7697-37-2
nitric acid

: 6280-88-2
4-chloro-2-nitro-benzoic acid

: 89-59-8
4-chloro-2-nitrotoluene

potassium permanganate: potassium permanganate

: 6280-88-2
4-chloro-2-nitro-benzoic acid

: 89-63-4
4-Chloro-2-nitroaniline

: 6280-88-2
4-chloro-2-nitro-benzoic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: durch Austausch von NH2 gegen CN nach Sandmeyer 2: concentrated sulfuric acid View Scheme
Multi-step reaction with 2 steps 2: sulfuric acid View Scheme
Multi-step reaction with 2 steps 1: copper (II)-sulfate; alkali cyanide; water; sulfuric acid; Wasser / Edukt 4: Natriumnitrit 2: aqueous sulfuric acid View Scheme

: 622-98-0
4-chloro(ethylbenzene)

: 6280-88-2
4-chloro-2-nitro-benzoic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: sulfuric acid; nitric acid 2: KMnO4 View Scheme

: 88-72-2
1-methyl-2-nitrobenzene

: 6280-88-2
4-chloro-2-nitro-benzoic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: SbCl5; chlorine / <40 2: nitric acid / 200 °C View Scheme

: 119-32-4
4-Methyl-3-nitroanilin

: 6280-88-2
4-chloro-2-nitro-benzoic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 2: KMnO4 View Scheme
Multi-step reaction with 2 steps 2: nitric acid / 200 °C View Scheme

4-Chloro-2-Nitrobenzoic Acid Chemical Properties

Molecular Formula: C₇H₄ClNO₄Molecular Weight: 201.56
EINECS: 228-483-5
Melting point: 141-143 °C(lit.)
Density: 1.5
Flash point: >100°C
Appearance: Slightly yellow powder.
Solubility in water: Very soluble
4-Chloro-2-nitrobenzoic acid's(6280-88-2) Synonyms: 2-Nitro-4-chlorobenzoic acid;4-CHLORO-2-NITROBENZOIC ACID;Benzoic acid, 4-chloro-2-nitro-;4-Chloro-2-nitrobenzoic acid, 97+%;4,2-CNBA;4-Chloro-2-Nitrobenzoic;4-CHLORO-2-NITROBENZOIC ACID 98+%
4-Chloro-2-nitrobenzoic acid's(6280-88-2) Structural formula:

4-Chloro-2-Nitrobenzoic Acid Uses

4-Chloro-2-nitrobenzoic acid(6280-88-2) can be used as pharmaceutical intermediate.

4-Chloro-2-Nitrobenzoic Acid Safety Profile

Safety Information for 4-Chloro-2-nitrobenzoic acid(6280-88-2)
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
Hazard Note Irritant
HS Code 29163900

4-Chloro-2-Nitrobenzoic Acid Specification

Stability and Reactivity for 4-Chloro-2-nitrobenzoic acid(6280-88-2)
【Disposal Code】4
【Incompatibilities】Oxidizing agents, strong bases.
【Stability】Stable at room temperature in closed containers under normal storage and handling conditions.
【Decomposition】Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.
Transport Information for 4-Chloro-2-nitrobenzoic acid(6280-88-2)
【HS Code】2916 39 00

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