Reported in EPA TSCA Inventory. Chlorophenol compounds are on the Community Right-To-Know List.

The IUPAC name of this chemical is 4-Chloro-3-methylphenol. With the CAS registry number 59-50-7 and EINECS 200-431-6, it is also named as Phenol,4-chloro-3-methyl-. In addition, the molecula formula is C₇H₇ClO and the molecular weight is 142.58. It belongs to the classes of Industrial/Fine Chemicals; Fluorobenzene; Biocides; Aromatic Phenols; Organics; Phenoles and thiophenoles; Highly Purified Reagents; Other Categories; Zone Refined Products. It is a kind of white or pink crystals.

Physical properties about this chemical are: (1)ACD/LogP: 2.89; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.89; (4)ACD/LogD (pH 7.4): 2.88; (5)#H bond acceptors: 1; (6)#H bond donors: 1; (7)#Freely Rotating Bonds: 1; (8)Polar Surface Area: 20.23 Å²; (9)Index of Refraction: 1.565; (10)Molar Refractivity: 37.85 cm³; (11)Molar Volume: 116 cm³; (12)Polarizability: 15 ×10^-24cm³; (13)Surface Tension: 42.1 dyne/cm; (14)Density: 1.228 g/cm³; (15)Flash Point: 93.4 °C; (16)Enthalpy of Vaporization: 49.09 kJ/mol; (17)Boiling Point: 235 °C at 760 mmHg; (18)Vapour Pressure: 0.0335 mmHg at 25°C.

Preparation of 4-Chloro-3-methylphenol: it can be prepared by m-cresol and dichlorosulfuryl. You can add the m-cresol into the dichlorosulfuryl slowly with stirring. The reaction temperature should be controlled at 30-50 °C. And the reaction time is 16 hours. After the reaction, you should wash the product with water, then wash it with sodium carbonate solution until alkaline and wash with hot water to neutral at last. After separating the oil, you should dry the product with anhydrous calcium chloride. Then vacuum distillation the product after filtering the desiccant.

Uses of 4-Chloro-3-methylphenol: it can be used as preservative of baby cosmetics and protein shampoo. It also can be used in organic synthesis, such as dyes and film preservatives. And it can be used to get 2,6-dibromo-4-chloro-3-methyl-phenol. This reaction will need reagent NBS. The reaction time is 0.1 minute at reaction temperature of 5 °C. The yield is about 50%. It is a kind of solid phase reaction.

When you are using this chemical, please be cautious about it as the following:
It is highly flammable and harmful in contact with skin and if swallowed. And it is toxic by inhalation, in contact with skin and if swallowed and very toxic to aquatic organisms and. It has very serious irreversible effects and risk of serious damage to the eyes. In addition, it may cause sensitization by skin contact. When you are using it, wear suitable protective clothing, gloves and eye/face protection. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. And you should avoid release to the environment and refer to special instructions / safety data sheets. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.). You also should keep away from sources of ignition and keep container tightly closed. After contact with skin, you should wash immediately with plenty of soap-suds.

You can still convert the following datas into molecular structure:
(1)SMILES: Oc1ccc(Cl)c(C)c1
(2)InChI: InChI=1/C7H7ClO/c1-5-4-6(9)2-3-7(5)8/h2-4,9H,1H3
(3)InChIKey: CFKMVGJGLGKFKI-UHFFFAOYAE

The toxicity data is as follows: