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4-Chlorotestosterone acetate

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Name

4-Chlorotestosterone acetate

EINECS 212-720-4
CAS No. 855-19-6 Density 1.19 g/cm3
PSA 43.37000 LogP 5.01650
Solubility N/A Melting Point 112-116°C(lit.)
Formula C21H29ClO3 Boiling Point 457.2 °C at 760 mmHg
Molecular Weight 364.912 Flash Point 155.7 °C
Transport Information N/A Appearance N/A
Safety Risk Codes R22; R43
Molecular Structure Molecular Structure of 855-19-6 (4-Chlorotestosterone acetate) Hazard Symbols Xn
Synonyms

Androst-4-en-3-one,4-chloro-17b-hydroxy-, acetate (8CI);Testosterone, 4-chloro-, acetate (6CI);17b-Acetoxy-4-chloroandrost-4-en-3-one;4-Chloro-17b-hydroxyandrost-4-en-3-one17-acetate;4-Chlorotestosterone 17-acetate;Anabolit;Chlorotestosterone acetate;Clostebol acetate;Macrobin;Megagrisevit;NSC 72159;Stearanabol;Sterabol;Steranabol;Test-anabol;Testomed;Turinabol;

Article Data 19

4-Chlorotestosterone acetate Synthetic route

1045-69-8

testosterone acetate

855-19-6

clostebol acetate

Conditions
ConditionsYield
Stage #1: testosterone acetate With 3,3-dimethyldioxirane In acetone at 20℃; for 8h; Epoxidation;
Stage #2: With Amberlyst 15; sodium chloride In acetone at 20℃; for 12h; Chlorination;
89%
With pyridine; sulfuryl dichloride for 1h; Product distribution; Ambient temperature; other steroids;
With pyridine; sulfuryl dichloride for 1h; Ambient temperature;
Multi-step reaction with 2 steps
1: N-chloro-succinimide, HN3 / CHCl3; 2-methyl-propan-2-ol
2: SiO2 / benzene
View Scheme
Multi-step reaction with 2 steps
1: N-chloro-succinimide, HN3 / CHCl3; 2-methyl-propan-2-ol
2: SiO2 / benzene
View Scheme
5012-85-1

17β-acetoxy-4β,5β-epoxyandrostan-3-one

855-19-6

clostebol acetate

Conditions
ConditionsYield
With hydrogenchloride; acetic acid
108-24-7

acetic anhydride

4-Cloro-3-(2'-cloro-etossi)-Δ3,5-androstadien-17β-olo-acetato

855-19-6

clostebol acetate

Conditions
ConditionsYield
(i) H2SO4, MeOH, (ii) /BRN= 385737/, Py; Multistep reaction;
18586-71-5

4β-Chlor-5β-azido-androstanol-17β-on-3-acetat

855-19-6

clostebol acetate

Conditions
ConditionsYield
With silica gel In benzene

4β-Chlor-5α-azido-androstanol-17β-on-3-acetat

855-19-6

clostebol acetate

Conditions
ConditionsYield
With silica gel In benzene
857-14-7

2α,4-Dichlor-testosteron-acetat

855-19-6

clostebol acetate

Conditions
ConditionsYield
With acetic acid; zinc In methanol

4-Cloro-Δ4-androsten-17β-ol-3-one acetato etilenchetale

855-19-6

clostebol acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: (i) POCl3, DMF, trichloroethene, (ii) NaOAc
2: (i) H2SO4, MeOH, (ii) /BRN= 385737/, Py
View Scheme
855-60-7

17β-acetoxy-2α-chloro-androst-4-en-3-one

855-19-6

clostebol acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: SO2Cl2, Py
2: Zn, AcOH / methanol
View Scheme
855-19-6

clostebol acetate

108-24-7

acetic anhydride

112551-54-9

3,17β-diacetoxy-4-chloro-androsta-3,5-diene

Conditions
ConditionsYield
With pyridine hydrochloride
855-19-6

clostebol acetate

123-62-6

propionic acid anhydride

114694-63-2

17β-acetoxy-4-chloro-3-propionyloxy-androsta-3,5-diene

Conditions
ConditionsYield
With pyridine hydrochloride

4-Chlorotestosterone acetate Chemical Properties

IUPAC Name: [(8R,9S,10R,13S,14S,17S)-4-Chloro-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] acetate
Synonyms of 4-Chlorotestosterone 17-acetate (CAS NO.855-19-6): 17beta-Acetoxy-4-chloroandrost-4-en-3-one ;  4-Chlorotestosterone acetate ; 4-Chlortestosterone acetate ; Alfa-Trofodermin ; Anabolit ; Chlorotestosterone acetate ; Clostebol acetate ; Clostebolacetate ; Clostene ; EINECS 212-720-4 ; Macrobin ; Megagrisevit ; NSC 72159 ; Stearanabol ; Sterabol ; Steranabol ; Test-anabol ; Testomed ; Turinabol ; Androst-4-en-3-one, 17-(acetyloxy)-4-chloro-, (17beta)- ; Androst-4-en-3-one, 4-chloro-17-beta-hydroxy-, acetate ; Testosterone, 4-chloro-, acetate ; DEA No. 4000
CAS NO: 855-19-6
Classification Code: Hormone ; Reproductive Effect
Molecular Formula of 4-Chlorotestosterone 17-acetate (CAS NO.855-19-6): C21H29ClO3
Molecular Weight: 364.9062
Molecular Structure:

Polar Surface Area: 43.37 Å2
Index of Refraction: 1.548
Molar Refractivity: 97.3 cm3
Molar Volume: 306.2 cm3
Surface Tension: 43.7 dyne/cm
Density of 4-Chlorotestosterone 17-acetate (CAS NO.855-19-6): 1.19 g/cm3
Flash Point: 155.7 °C
Enthalpy of Vaporization: 71.73 kJ/mol
Boiling Point: 457.2 °C at 760 mmHg
Vapour Pressure: 1.52E-08 mmHg at 25°C

4-Chlorotestosterone acetate Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 2780ug/kg (2.78mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 9, Pg. 759, 1967.

4-Chlorotestosterone acetate Safety Profile

A poison by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic vapors of Cl.

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