Basic information
- Name:
4-Hydroxypiperidine
- CAS No.:
5382-16-1
- Molecular Structure:
- Formula:
- C5H11NO
- Molecular Weight:
- 101.15
- Synonyms:
- Piperidin-4-ol;4-Piperidinol;3,4,5,6-tetrahydro-2H-pyridin-4-ol;4-Hydroxypiperidin;
- EINECS:
- 226-373-1
- Density:
- 1.016 g/cm3
- Melting Point:
- 86-90 °C
- Boiling Point:
- 222 °C at 760 mmHg
- Flash Point:
- 107.8 °C
- Solubility:
- soluble in water
- Appearance:
- yellow to yellow-orange wet solid
- Hazard Symbols:
Xi, 
C- Risk Codes:
- 36/37/38-34
- Safety Description:
- 26-36-37/39-45-36/37/39-27 Details
- Transport Information:
- UN 3263
Famous Chemical Enterprises
-
Livzon -
Total -
Shell -
Dupont -
Exxonmobil -
Akzonobel -
Basf -
Bayer -
BP
Please post your buying leads,so that our qualified suppliers will soon
contact you!
*Required Fields
Specification
The IUPAC name of 4-Hydroxypiperidine is piperidin-4-ol. With the CAS registry number 5382-16-1, it is also named as 4-Piperidinol; NSC 62083; AI3-39158. The product's categories are alcohols and derivatives, amines and anilines, piperidines, piperidones, piperazines, pyrans, piperidines & piperazines, piperidine, heterocyclic compounds and pyrans and piperidines & piperazines. It is yellow to yellow-orange wet solid which is soluble in water.
The other characteristics of this product can be summarized as: (1)ACD/LogP: -0.52; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -3.61; (4)ACD/LogD (pH 7.4): -3.33; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 2; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 1; (12)Index of Refraction: 1.474; (13)Molar Refractivity: 27.99 cm3; (14)Molar Volume: 99.4 cm3; (15)Polarizability: 11.09×10-24 cm3; (16)Surface Tension: 33.7 dyne/cm; (17)Enthalpy of Vaporization: 53.31 kJ/mol; (18)Vapour Pressure: 0.0214 mmHg at 25°C; (19)Exact Mass: 101.084064; (20)MonoIsotopic Mass: 101.084064; (21)Topological Polar Surface Area: 32.3; (22)Heavy Atom Count: 7.
Uses of 4-Hydroxypiperidine: 1. It can react with 2-bromomethyl-[1,3]dioxolane to get 1-(1,3-dioxolan-2-ylmethyl)-4-piperidinol. This reaction needs reagent K2CO3 and solvent acetonitrile by heating. The reaction time is 15 hours. The yield is 83.5%.
.gif)
2. It also reacts with 4-chloromethyl-[1,3]dioxolane to obtain 1-[1,3]dioxolan-4-ylmethyl-piperidin-4-ol. This reaction needs reagent K2CO3 and solvent acetonitrile by heating. The reaction time is 16 hours. The yield is 56.4%.
.gif)
When you are using this chemical, please be cautious about it as the following:
It can causes burns. And it is irritating to eyes, respiratory system and skin. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Take off immediately all contaminated clothing. If you want to contact this product, you must wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
People can use the following data to convert to the molecule structure.
1. SMILES: OC1CCNCC1;
2. InChI: InChI=1/C5H11NO/c7-5-1-3-6-4-2-5/h5-7H,1-4H2.
