4-Thiazolecarboxylic acid

IUPAC Name: 1,3-thiazole-4-carboxylic acid (3973-08-8)
Synonyms: 1,3-Thiazole-4-carboxylic acid ; Akos bb-9161 ; 4-Carboxythiazole ; 4-Thiazolecarboxylic acid ; Timtec-bb sbb010166 ; Thiazole-4-carboxylic acid ; 4-Thiazolecarboxylic acid 3973-8-8 ; 1,3-Thiazole-4-carboxylic acid 3973-8-8
CAS: 3973-08-8
MF: C₄H₃NO₂S
MW: 129.14
MS:
Product Categories: blocks ; Carboxes ; Thiazoles ; Sulphur Derivatives ; Carboxylic Acids ; Thiazoles, Isothiazoles &Benzothiazoles ; Carboxylic Acids ; Thiazoles, Isothiazoles & Benzothiazoles ; Building Blocks ; Heterocyclic Building Blocks
Mol File: 3973-08-8.mol
Surface Tension: 72 dyne/cm  Density: 1.525 g/cm³ 
Flash Point: 146.9 °C  Enthalpy of Vaporization: 59.21 kJ/mol 
Boiling Point: 319.2 °C at 760 mmHg  Vapour Pressure: 0.000143 mmHg at 25°C 
MP:195-199 °C(lit.)

1.4-Thiazolecarboxylic acid (93973-08-8) is an intermediate of fungicide thiabendazole. 
2.4-Thiazolecarboxylic acid (93973-08-8) is used as a medicine, pesticide intermediates, organic synthesis reagents .

Its preparation method is to use formamide with P2S5 in ethylene glycol dimethyl ether (CH₃OCH₂CH₂OCH₃) reaction to obtain thiocarboxamide (HCSNH₂), and then,  halogenate with pyruvate  for product.

Hazard Codes:  Xi
Risk Statements:  43
43: 4-Thiazolecarboxylic acid (93973-08-8) may cause sensitization by skin contact 
Safety Statements : 36/37
36/37:  Wear suitable protective clothing and gloves  
WGK Germany: 3

4-Thiazolecarboxylic acid (93973-08-8) is a colorless solid, not dissolve in water.