5'-Uridylic acid,sodium salt (1:2) (3387-36-8),5'-Uridylic acid,sodium salt (1:2) (3387-36-8) Manufacturers & Suppliers,Synthesis,MSDS

Basic information

Name:
5'-Uridylic acid,sodium salt (1:2)
Superlist Name:
Disodium uridine-5'-monophosphate
CAS No.:
3387-36-8
Molecular Structure:
Formula:
C₉H₁₁N₂Na₂O₉P
Molecular Weight:
368.15
Synonyms:
5'-Uridylicacid, disodium salt (7CI,8CI,9CI);5'-UMP disodium salt;Disodium 5'-UMP;Disodium 5'-uridylate;Disodium UMP;Disodium uridine 5'-phosphate;NSC 20257;UMP disodium salt;Uridine5'-(dihydrogen phosphate) disodium salt;Uridine 5'-monophosphate disodiumsalt;Uridylic acid disodium salt;
EINECS:
222-211-9
Melting Point:
208-210 °C
Solubility:
40 g/100 mL (20 °C) in water
Appearance:
Crystalline
Hazard Symbols:
Xi
Risk Codes:
36/37/38
Safety Description:
22-24/25-36-26 Details

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Chemistry

IUPAC Name: Disodium [(2R,3S,4S,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
Systematic of 5'-Uridylic acid,sodium salt (1:2) (CAS NO.3387-36-8): 5'-UMP disodium ; CCRIS 6562 ; Disodium 5'-UMP ; Disodium 5'-uridylate ; Disodium UMP ; Disodium uridine 5'-monophosphate ; Disodium uridine 5'-phosphate ; EINECS 222-211-9 ; NSC 20257 ; Uridine 5'MP, disodium salt ; Uridine-5-monophosphate disodium salt
CAS NO: 3387-36-8
Classification Code: Agricultural Chemical ; Growth regulator / Fertilizer
Molecular Formula of 5'-Uridylic acid,sodium salt (1:2) (CAS NO.3387-36-8): C₉H₁₁N₂Na₂O₉P
Molecular Weight: 368.1449
Molecular Structure:

Melting Point: 208-210 °C
Product Categories: Biochemistry ; Nucleosides, Nucleotides & Related Reagents ; Nucleotides and their analogs ; Nucleic acids
H bond acceptors: 11
H bond donors: 3
Freely Rotating Bonds: 10
Polar Surface Area of 5'-Uridylic acid,sodium salt (1:2) (CAS NO.3387-36-8): 153.67 Å²

Uses

5'-Uridylic acid,sodium salt (1:2) (CAS NO.3387-36-8) is used as flavoring agent: nucleotide added to the milk to increase volume to make it closer to human milk composition, increase resistance to infants and young children. And it can be used as auxiliary liver disease drug. It also used as production of intermediate nucleic acid drugs asn health food and biochemical reagents. And it for the manufacture of uridine triphosphate (UTP), poly gland urine, drugs such Furtulon.

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	3394mg/kg (3394mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 22, Pg. 618, 1975.
mouse	LD50	oral	> 12gm/kg (12000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 22, Pg. 618, 1975.
mouse	LD50	subcutaneous	3698mg/kg (3698mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 22, Pg. 618, 1975.
rat	LD50	intraperitoneal	3111mg/kg (3111mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 22, Pg. 618, 1975.
rat	LD50	oral	> 12gm/kg (12000mg/kg)		Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 22, Pg. 618, 1975.
rat	LD50	subcutaneous	> 6gm/kg (6000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SKIN AND APPENDAGES (SKIN): "DERMATITIS, IRRITATIVE: AFTER SYSTEMIC EXPOSURE"	Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 22, Pg. 618, 1975.

Safety Profile

Hazard Codes: Irritant Xi
Risk Statements: 36/37/38
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 22-24/25-36-26
S22: Do not breathe dust.
S24/25: Avoid contact with skin and eyes.
S36: Wear suitable protective clothing.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 2
RTECS: YU7975000
F: 10-21