The 5-Amino-2-methoxypyridine with cas registry number of 6628-77-9 belongs to the classes in Pyridine; Pyridines, Pyrimidines, Purines and Pteredines; Pyridine series; Pyridines derivates; Pyridines; Boronic Acid; C6; Heterocyclic Building Blocks; Amino-pyridine series. Its EINECS registry number is 229-612-8. This chemical is also known as Pyridine, 5-amino-2-methoxy- and 6-Methoxy-3-pyridylamine which is also its IUPAC name.

Physical properties about this chemical are: (1)ACD/LogP: 0.47; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.46; (4)ACD/LogD (pH 7.4): 0.47; (5)ACD/BCF (pH 5.5): 1.29; (6)ACD/BCF (pH 7.4): 1.34; (7)ACD/KOC (pH 5.5): 41.42; (8)ACD/KOC (pH 7.4): 42.98; (9)#H bond acceptors: 3; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 2; (12)Index of Refraction: 1.56 ; (13)Molar Refractivity: 35.25 cm³; (14)Molar Volume: 108.9 cm³; (15)Surface Tension: 46.1 dyne/cm; (16)Density: 1.139 g/cm³; (17)Flash Point: 109.5 °C; (18)Enthalpy of Vaporization: 50.27 kJ/mol; (19)Boiling Point: 264.8 °C at 760 mmHg; (20)Vapour Pressure: 0.00951 mmHg at 25°C.

Preparation of 5-Amino-2-methoxypyridine: this chemical can be made by 2-methoxy-5-nitro-pyridine by using reagents Me₃SiSNa and 1,3-dimethyl2-imidazolidinone under the reaction temperature 185 ℃. The reaction time is 3 hours. The yield is 70%.

Uses of 5-Amino-2-methoxypyridine: it can used to prepare 3-amino-2-bromo-6-methoxypyridine by using reagents NaOAc and Br₂, solvent Acetic acid with reaction time 20 min. The yield is 60%.

When you are using this chemical, please be cautious about it as the following:
This chemical is harmful if swallowed and irritating to eyes, respiratory system and skin. Wear suitable protective clothing, gloves and eye/face protection during using it. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: COC1=NC=C(C=C1)N;
(2)InChI: InChI=1S/C6H8N2O/c1-9-6-3-2-5(7)4-8-6/h2-4H,7H2,1H3;
(3)InChIKey: UUVDJIWRSIJEBS-UHFFFAOYSA-N

The toxicity data is as follows: