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5-Ethyl-5-phenylimidazolidine-2,4-dione

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Name

5-Ethyl-5-phenylimidazolidine-2,4-dione

EINECS 211-150-3
CAS No. 631-07-2 Density 1.173 g/cm3
PSA 58.20000 LogP 1.78890
Solubility 804.4mg/L(37 oC) Melting Point 195-200°C
Formula C11H12 N2 O2 Boiling Point 342.72°C (rough estimate)
Molecular Weight 204.228 Flash Point N/A
Transport Information N/A Appearance Off-White Solid
Safety 26 Risk Codes 22-36/37/38
Molecular Structure Molecular Structure of 631-07-2 ((+/-)-5-ETHYL-5-PHENYLHYDANTOIN) Hazard Symbols HarmfulXn
Synonyms

Hydantoin,5-ethyl-5-phenyl- (6CI,7CI,8CI); (RS)-5-Ethyl-5-phenyl-2,4-imidazolidinedione;5-Ethyl-5-phenyl-2,4-imidazolidinedione; 5-Ethyl-5-phenylhydantoin;5-Phenyl-5-ethylhydantoin; Desmethylmephenytoin; Ethylphenylhydantoin; NSC150466; NSC 33388; Nirvanol; Normephenytoin

Article Data 1

5-Ethyl-5-phenylimidazolidine-2,4-dione Chemical Properties

IUPAC Name: 5-Ethyl-5-phenylimidazolidine-2,4-dione
The MF of 5-Ethyl-5-phenylimidazolidine-2,4-dione (CAS NO.631-07-2) is C11H12N2O2.

                                          
The MW of 5-Ethyl-5-phenylimidazolidine-2,4-dione (CAS NO.631-07-2) is 204.23.
Synonyms of 5-Ethyl-5-phenylimidazolidine-2,4-dione (CAS NO.631-07-2): 5-Ethyl-5-phenyl-2,4-imidazolidinedione ; Desmethyl mephenytoin ; (+/-)-Nirvanol ; N-Desmethylmephentoin
Product Categories: Various Metabolites and Impurities;Hydantoins & Derivatives
Index of Refraction: 1.538 
Apperance: Off-White Solid
EINECS: 211-150-3
Density: 1.173 g/ml 
Melting Point: 195-200 °C
Storage temp: 2-8 °C

5-Ethyl-5-phenylimidazolidine-2,4-dione Uses

 5-Ethyl-5-phenylimidazolidine-2,4-dione (CAS NO.631-07-2) is used as an anticonvulsant, hypnotic and a metabolite of mephenytoin.

5-Ethyl-5-phenylimidazolidine-2,4-dione Toxicity Data With Reference

1.    

orl-mus LDLo:500 mg/kg

    LDTU**    Narkoseversuche mit Hoheren Alkoholen und Stickstoffderivaten, Fritz Leube Dissertation .(Pharmakologischen Institut der Universitat Tubingen,Germany.: 1931)
2.    

scu-mus LDLo:500 mg/kg

    HDTU**    Pharmakologische Prufung von Analgetika, Gunter Herrlen Dissertation .(Pharmakologischen Institut der Universitat Tubingen,Germany.: 1933)
3.    

scu-dog LDLo:200 mg/kg

    HBAMAK    “Abdernalden’s Handbuch der Biologischen Arbeitsmethoden.“ 4 (1935),1289.
4.    

scu-frg LDLo:100 mg/kg

    HBAMAK    “Abdernalden’s Handbuch der Biologischen Arbeitsmethoden.“ 4 (1935),1289.

5-Ethyl-5-phenylimidazolidine-2,4-dione Safety Profile

Poison by subcutaneous route. Moderately toxic by ingestion. A skin, eye, and mucous membrane irritant. Combustible when exposed to heat or flame; can react with oxidizing materials. When heated to decomposition it emits toxic fumes such as NOx.Safety information of 5-Ethyl-5-phenylimidazolidine-2,4-dione (CAS NO.631-07-2):
Hazard Codes  HarmfulXn
Risk Statements 
22 Harmful if swallowed
36/37/38 Irritating to eyes, respiratory system and skin
Safety Statements 
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
WGK Germany  2
RTECS  MU2452000

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