Welcome to LookChem.com Sign In|Join Free

Product Name

  • or
Home > Products > 

6,7-Dihydroxy-4-methylcoumarin

  • Name 6,7-Dihydroxy-4-methylcoumarin
  • EINECS208-470-0
  • CAS No. 529-84-0
  • Density1.456 g/cm3
  • PSA70.67000
  • LogP1.51260
  • SolubilityDMF: soluble in water
  • Melting Point274-276 °C(lit.)
  • FormulaC10H8 O4
  • Boiling Point455.5 °C at 760 mmHg
  • Molecular Weight192.171
  • Flash Point190.7 °C
  • Transport InformationN/A
  • AppearanceYellow needle crystal
  • SafetyModerately toxic by ingestion. Slightly toxic by intraperitoneal route. When heated to decomposition it emits acrid smoke and irritating vapors.
  • Risk Codes36/37/38
  • Molecular Structure
    Molecular Structure of 529-84-0 (4-METHYLESCULETIN)
  • Hazard SymbolsIrritantXi
  • SynonymsIrritantXi
  • Article Data30

6,7-Dihydroxy-4-methylcoumarin Chemical Properties

IUPAC Name: 6,7-Dihydroxy-4-methylchromen-2-one
Synonyms : 6,7-Dihydroxy-4-methyl-2H-chromen-2-one ; 2H-1-benzopyran-2-one, 6,7-dihydroxy-4-methyl- ; 4-Methyl-6, 7-dihydroxycoumarin ; 4-Methyl-6,7-dihydroxycoumarin ; 4-Methylaesculetin ; 4-Methylesculetin ; 4-Methylesculetol
Molecular Structure :
Molecular Formula : C10H8O4
Molecular Weight : 192.17
CAS NO: 529-84-0
EINECS : 208-470-0
BRN 162550
Product Categories: Coumarins
Index of Refraction: 1.651
Surface Tension: 63.4 dyne/cm
Density: 1.456 g/cm3
Flash Point: 190.7 °C
Enthalpy of Vaporization: 74.27 kJ/mol
Boiling Point: 455.5 °C at 760 mmHg
Vapour Pressure: 6.46E-09 mmHg at 25°C
Melting point: 274-276 °C(lit.)
Appearance: 4-Methylesculetin (CAS NO. 529-84-0) is yellow needle crystal.
Solubility: 4-Methylesculetin (CAS NO. 529-84-0) is soluble in hot water, alcohol, acetic acid, concentrated sulfuric acid and dilute alkali, the solution appears blue fluorescence, green in case of ferric chloride.

6,7-Dihydroxy-4-methylcoumarin Uses

 4-Methylesculetin (CAS NO. 529-84-0) is used as a fluorescent indicator.

6,7-Dihydroxy-4-methylcoumarin Production

Phenyl triacetate is generated from reaction of p-benzoquinone with acetic anhydride in the presence of concentrated acid . reaction of phenyl triacetate with ethyl acetoacetate under the action of the sulfuric acid, the reactant poured into the ice water, precipitation of crude methyl 7 clovertei, re-crystallization the crystallization which is filtered out, then 4-Methylesculetin (CAS NO. 529-84-0) is derived.

6,7-Dihydroxy-4-methylcoumarin Toxicity Data With Reference

1.    

ipr-rat LD50:5130 mg/kg

    THERAP    Therapie. 20 (1965),879.
2.    

orl-mus LD50:3200 mg/kg

    MPHEAE    Medicina et Pharmacologia Experimentalis. 17 (1967),497.

6,7-Dihydroxy-4-methylcoumarin Consensus Reports

Reported in EPA TSCA Inventory.

6,7-Dihydroxy-4-methylcoumarin Safety Profile

Hazard Codes IrritantXi
Risk Statements 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements 26-36 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
WGK Germany 2
RTECS GN6384500
F 8

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 529-84-0
Related Products

Hot Products

Post a RFQ