IUPAC Name: 6,7-Dihydroxy-4-methylchromen-2-one
Synonyms : 6,7-Dihydroxy-4-methyl-2H-chromen-2-one ; 2H-1-benzopyran-2-one, 6,7-dihydroxy-4-methyl- ; 4-Methyl-6, 7-dihydroxycoumarin ; 4-Methyl-6,7-dihydroxycoumarin ; 4-Methylaesculetin ; 4-Methylesculetin ; 4-Methylesculetol
Molecular Structure :
Molecular Formula : C₁₀H₈O₄
Molecular Weight : 192.17
CAS NO: 529-84-0
EINECS : 208-470-0
BRN 162550
Product Categories: Coumarins
Index of Refraction: 1.651
Surface Tension: 63.4 dyne/cm
Density: 1.456 g/cm³
Flash Point: 190.7 °C
Enthalpy of Vaporization: 74.27 kJ/mol
Boiling Point: 455.5 °C at 760 mmHg
Vapour Pressure: 6.46E-09 mmHg at 25°C
Melting point: 274-276 °C(lit.)
Appearance: 4-Methylesculetin (CAS NO. 529-84-0) is yellow needle crystal.
Solubility: 4-Methylesculetin (CAS NO. 529-84-0) is soluble in hot water, alcohol, acetic acid, concentrated sulfuric acid and dilute alkali, the solution appears blue fluorescence, green in case of ferric chloride.

 4-Methylesculetin (CAS NO. 529-84-0) is used as a fluorescent indicator.

Phenyl triacetate is generated from reaction of p-benzoquinone with acetic anhydride in the presence of concentrated acid . reaction of phenyl triacetate with ethyl acetoacetate under the action of the sulfuric acid, the reactant poured into the ice water, precipitation of crude methyl 7 clovertei, re-crystallization the crystallization which is filtered out, then 4-Methylesculetin (CAS NO. 529-84-0) is derived.

Reported in EPA TSCA Inventory.

Hazard Codes Xi
Risk Statements 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements 26-36 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
WGK Germany 2
RTECS GN6384500
F 8