Basic information
- Name:
6-Chloronicotinic acid
- CAS No.:
5326-23-8
- Molecular Structure:

- Formula:
- C6H4ClNO2
- Molecular Weight:
- 157.56
- Synonyms:
- 6-Chloro-3-pyridinecarboxylic acid;6-chloropyridine-3-carboxylate;6-chloropyridine-3-carboxylic acid;3-Pyridinecarboxylic acid, 6-chloro-;6-Cholre Nicotinic Acid;6-Chloro nicotinic acid;
- EINECS:
- 226-201-5
- Density:
- 1.47 g/cm3
- Melting Point:
- 190 °C (dec.)(lit.)
- Boiling Point:
- 330.1 °C at 760 mmHg
- Flash Point:
- 153.4 °C
- Appearance:
- Off-white to beige crystalline powder
- Hazard Symbols:
Xi- Risk Codes:
- 36/37/38
- Safety Description:
- 26-36-24/25-37/39 Details
- particular:
- particular
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Chemistry
Molecular Structure:
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Molecular Formula: C6H4ClNO2
Molecular Weight: 157.5545
IUPAC Name: 6-Chloropyridine-3-carboxylic acid
Synonyms of 6-Chloronicotinic acid (CAS NO.5326-23-8): 6-Chloro-3-pyridinecarboxylic acid ; EINECS 226-201-5 ; NSC 277 ; 3-Pyridinecarboxylic acid, 6-chloro-
CAS NO: 5326-23-8
Product Categories: Nitrogen cyclic compounds ; blocks ; Carboxes ; Pyridines ; Pyridine ; Carboxylic Acids ; Organic acids ; Chloropyridines ; Halopyridines ; Carboxylic Acids ; Picolinic acid series
Melting point: 190 °C
Index of Refraction: 1.59
Molar Refractivity: 36.16 cm3
Molar Volume: 107.1 cm3
Surface Tension: 61 dyne/cm
Density: 1.47 g/cm3
Flash Point: 153.4 °C
Enthalpy of Vaporization: 60.44 kJ/mol
Boiling Point: 330.1 °C at 760 mmHg
Vapour Pressure: 6.84E-05 mmHg at 25°C
Uses
6-Chloronicotinic acid (CAS NO.5326-23-8) is used as building block for different chemical synthesis. Product Data Sheet.
Toxicity Data With Reference
1. RTECS#: CAS# 5326-23-8: None listed
2. LD50/LC50: RTECS: Not available.
3. Carcinogenicity: 6-Chloronicotinic acid - Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.
4. Other: The toxicological properties have not been fully investigated.
Consensus Reports
6-Chloronicotinic acid (CAS NO.5326-23-8) is reported in EPA TSCA Inventory.
Safety Profile
Hazard Codes of 6-Chloronicotinic acid (CAS NO.5326-23-8):
Xi
Risk Statements: 36/37/38
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36-24/25-37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36: Wear suitable protective clothing.
S24/25: Avoid contact with skin and eyes.
S37/39: Wear suitable gloves and eye/face protection.
WGK Germany: 3
Hazard Note: Irritant
TSCA: T
HazardClass: IRRITANT
HS Code: 29333999
Specification
1、Fire Fighting Measures of 6-Chloronicotinic acid (CAS NO.5326-23-8)
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use WATER spray, dry chemical, CARBON dioxide, or chemical foam.
2、Handling and Storage
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage: Store in a cool, dry place. Store in a tightly closed container.

