Basic Information | Post buying leads | Suppliers | Cas Database |
Name |
6H-Purin-6-one,2,8-diamino-1,9-dihydro- |
EINECS | N/A |
CAS No. | 28128-41-8 | Density | 2.53 g/cm3 |
PSA | 126.47000 | LogP | -0.02700 |
Solubility | N/A | Melting Point |
>330°C (dec.) |
Formula | C5H6N6O | Boiling Point | 625.9 °C at 760 mmHg |
Molecular Weight | 166.142 | Flash Point | 332.3 °C |
Transport Information | N/A | Appearance | N/A |
Safety | Risk Codes | N/A | |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
6H-Purin-6-one,2,8-diamino-1,7-dihydro- (9CI);Hypoxanthine, 2,8-diamino- (8CI);8-Aminoguanine;NSC 23170;Hydrazinecarboximidamide; |
Article Data | 8 |
8-<(4-bromophenyl)azo>guanine
8-aminoguanine
Conditions | Yield |
---|---|
With sodium dithionite In sodium hydroxide at 90℃; for 48h; pH 9; | 60% |
8-nitroguanine
8-aminoguanine
Conditions | Yield |
---|---|
With sodium disulfite In water at 20℃; for 0.166667h; | |
With sodium dithionite Product distribution; |
2-amino-1,9-dihydro-6H-purin-6-one
8-aminoguanine
Conditions | Yield |
---|---|
Stage #1: 2-amino-1,9-dihydro-6H-purin-6-one With 4-chlorophenyldiazonium salt Stage #2: With sodium hydrogensulfite | |
Multi-step reaction with 2 steps 1: peroxynitrite / aq. phosphate buffer / 0.08 h / 20 °C / pH 7 2: sodium dithionite View Scheme | |
Multi-step reaction with 2 steps 1: aq. HCl; ammonium formate; peroxonitrite / 0.03 h / 20 °C / pH 6.8 - 7.0 2: sodium hydrosulfite / H2O / 0.17 h / 20 °C View Scheme | |
Multi-step reaction with 2 steps 1: 75 percent / aq. NaOH / 0.25 h / 0 °C / pH 10-11 2: 60 percent / sodium dithionite / aq. NaOH / 48 h / 90 °C / pH 9 View Scheme |
8-aminoguanosine
8-aminoguanine
Conditions | Yield |
---|---|
With hydrogenchloride In water at 70℃; for 1h; |
8-aminoguanine
Conditions | Yield |
---|---|
With N,N-dimethyl-aniline; trichlorophosphate for 0.5h; Heating; | 63% |
Conditions | Yield |
---|---|
With trans-N-deoxyribosylase from Lactobacillus helveticus In water at 37℃; for 15h; Product distribution; trans-deoxyribosylation; Enzymatic reaction; product analyzed by HPLC; | 58 % Chromat. |
8-aminoguanine
N,N-dimethylformamide dineopentyl acetal
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide |
8-aminoguanine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: dimethylformamide 2: NaH / dimethylformamide 3: Me3SiBr / acetonitrile View Scheme |
8-aminoguanine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: dimethylformamide 2: NaH / dimethylformamide 3: Me3SiBr / acetonitrile View Scheme |
8-aminoguanine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: dimethylformamide 2: NaH / dimethylformamide View Scheme |
The CAS registry number of 6H-Purin-6-one,2,8-diamino-1,9-dihydro- is 28128-41-8. It belongs to the product categories of Nucleotides and Nucleosides; Bases & Related Reagents. This chemical is also named as 8-Amino guanine. In addition, its molecular formula is C5H6N6O and molecular weight is 166.14. Its IUPAC name is called 2,8-diamino-3,7-dihydropurin-6-one.
Physical properties about 6H-Purin-6-one,2,8-diamino-1,9-dihydro- are: (1)ACD/LogP: -1.13; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): -1.19; (4)ACD/LogD (pH 7.4): -1.14; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 5.09; (8)ACD/KOC (pH 7.4): 5.74; (9)#H bond acceptors: 7; (10)#H bond donors: 6; (11)#Freely Rotating Bonds: 0 ; (12)Index of Refraction: 2.228; (13)Molar Refractivity: 37.38 cm3; (14)Molar Volume: 65.6 cm3; (15)Surface Tension: 169.2 dyne/cm; (16)Density: 2.53 g/cm3; (17)Flash Point: 332.3 °C; (18)Enthalpy of Vaporization: 92.66 kJ/mol; (19)Boiling Point: 625.9 °C at 760 mmHg.
You can still convert the following datas into molecular structure:
(1)SMILES: O=C2/N=C(\Nc1nc(nc12)N)N
(2)InChI: InChI=1/C5H6N6O/c6-4-8-1-2(9-4)10-5(7)11-3(1)12/h(H6,6,7,8,9,10,11,12)
(3)InChIKey: WYDKPTZGVLTYPG-UHFFFAOYAL