The 8-Aminoquinoline, with the CAS registry number 578-66-5, is also known as 8-Quinolinamine. It belongs to the product categories of Quinolines, Quinazolines and Derivatives; Quinoline & Isoquinoline; Quinolines; Aminoquinolines; Quinoline. Its EINECS registry number is 209-427-9. This chemical's molecular formula is C₉H₈N₂ and molecular weight is 144.17. What's more, both its IUPAC name and systematic name are the same which is called Quinolin-8-amine. It should be stored in a sealed place and keep away from light. The 8-Aminoquinoline family of drugs contains three members, primaquine, tafenoquine and pamaquine and are used in the treatment of malaria. They may be used to eradicate malaria hypnozoites from the liver and have both been used for malaria prophylaxis.

Physical properties about 8-Aminoquinoline are: (1)ACD/LogP: 1.88; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.85; (4)ACD/LogD (pH 7.4): 1.87; (5)ACD/BCF (pH 5.5): 14.68; (6)ACD/BCF (pH 7.4): 15.66; (7)ACD/KOC (pH 5.5): 233.77; (8)ACD/KOC (pH 7.4): 249.34; (9)#H bond acceptors: 2; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 16.13 Å²; (13)Index of Refraction: 1.708; (14)Molar Refractivity: 46.42 cm³; (15)Molar Volume: 119 cm³; (16)Surface Tension: 59.8 dyne/cm; (17)Density: 1.21 g/cm³; (18)Flash Point: 171.5 °C; (19)Enthalpy of Vaporization: 52.92 kJ/mol; (20)Boiling Point: 289.8 °C at 760 mmHg; (21)Vapour Pressure: 0.00215 mmHg at 25 °C.

Preparation of 8-Aminoquinoline: this chemical can be prepared by 8-Nitro-quinoline. This reaction needs reagents sulfur, NH₃ at temperature of 100 °C.

Uses of 8-Aminoquinoline: it is used to produce other chemicals. For example, it can react with Acetic acid anhydride to get N-[8]Quinolyl-acetamide. The reaction occurs with reagent benzene at ambient temperature for 1 hour. The yield is 91 %.

When you are dealing with this chemical, you should be very careful. This chemical is inflammation to the skin, eyes and respiratory system or other mucous membranes. It is harmful by inhalation, in contact with skin and if swallowed. And it may have irreversible effects. Therefore, you should wear suitable protective clothing, gloves and eye/face protection. In case of contacting with eyes, you should rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1) SMILES: n1cccc2cccc(N)c12
(2) InChI: InChI=1S/C9H8N2/c10-8-5-1-3-7-4-2-6-11-9(7)8/h1-6H,10H2
(3) InChIKey: WREVVZMUNPAPOV-UHFFFAOYSA-N