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8-Hydroxyguanosine

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Name

8-Hydroxyguanosine

EINECS N/A
CAS No. 3868-31-3 Density 2.43g/cm3
PSA 179.74000 LogP -2.39990
Solubility N/A Melting Point 232-235°C
Formula C10H13 N5 O6 Boiling Point °Cat760mmHg
Molecular Weight 299.243 Flash Point °C
Transport Information N/A Appearance N/A
Safety Mutation data reported. When heated to decomposition it emits toxic vapors of NOx. Risk Codes N/A
Molecular Structure Molecular Structure of 3868-31-3 (8-HYDROXYGUANOSINE) Hazard Symbols N/A
Synonyms

Purine-6,8(1H,9H)-dione,2-amino-9-b-D-ribofuranosyl- (7CI,8CI);8-Hydroxyguanosine; 8-Oxo-7,8-dihydroguanosine; 8-Oxoguanosine; NSC 90393

Article Data 2

8-Hydroxyguanosine Chemical Properties

Product Name: 8-Hydroxyguanosine (CAS NO.3868-31-3)


Molecular Formula: C10H13N5O6
Molecular Weight: 299.24g/mol
Mol File: 3868-31-3.mol
Melting Point: 232-235°C
Density: 2.43 g/cm3
Surface Tension: 142.6 dyne/cm
Enthalpy of Vaporization:
XLogP3-AA: -3.6
H-Bond Donor: 6
H-Bond Acceptor: 8
Structure Descriptors of 8-Hydroxyguanosine (CAS NO.3868-31-3):
  IUPAC Name: 2-amino-9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,7-dihydropurine-6,8-dione
  Canonical SMILES: C(C1C(C(C(O1)N2C3=C(C(=O)N=C(N3)N)NC2=O)O)O)O
  InChI: InChI=1S/C10H13N5O6/c11-9-13-6-3(7(19)14-9)12-10(20)15(6)8-5(18)4(17)2(1-16)21-8/h2,4-5,8,16-18H,1H2,(H,12,20)(H3,11,13,14,19) 
  InChIKey: FPGSEBKFEJEOSA-UHFFFAOYSA-N
Product Categories: Nucleotides and Nucleosides; Bases & Related Reagents; Labeling and Diagnostics Reagents; Nucleotides

8-Hydroxyguanosine Uses

 8-Hydroxyguanosine (CAS NO.3868-31-3) is a nucleoside which is an oxidative derivative of guanosine. Measurement of the levels of 8-hydroxyguanosine is used as a biomarker of oxidative stress.

8-Hydroxyguanosine Toxicity Data With Reference

1.    

sce-hmn-lym 100 nmol/L

    MUREAV    Mutation Research. 403 (1998),223.

8-Hydroxyguanosine Safety Profile

Mutation data reported. When heated to decomposition it emits toxic vapors of NOx.

8-Hydroxyguanosine Specification

 8-Hydroxyguanosine , its CAS NO. is 3868-31-3, the synonyms are 2-Amino-9-beta-D-ribofuranosylpurine-6,8(1H,9H)-dione ; 8-Oxo-2'-deoxyguanosine ; 8-Oxoguanosine ; CCRIS 8242 ; NSC 90393 ; Guanosine, 7,8-dihydro-8-oxo- (9CI) ; Purine-6,8(1H,9H)-dione, 2-amino-9-beta-D-ribofuranosyl- .

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