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8-Hydroxyguanosine

  • Name 8-Hydroxyguanosine
  • EINECSN/A
  • CAS No. 3868-31-3
  • Density2.43g/cm3
  • PSA179.74000
  • LogP-2.39990
  • SolubilityN/A
  • Melting Point232-235°C
  • FormulaC10H13 N5 O6
  • Boiling Point°Cat760mmHg
  • Molecular Weight299.243
  • Flash Point°C
  • Transport InformationN/A
  • AppearanceN/A
  • SafetyMutation data reported. When heated to decomposition it emits toxic vapors of NOx.
  • Risk CodesN/A
  • Molecular Structure
    Molecular Structure of 3868-31-3 (8-HYDROXYGUANOSINE)
  • Hazard SymbolsN/A
  • SynonymsN/A
  • Article Data2

8-Hydroxyguanosine Chemical Properties

Product Name: 8-Hydroxyguanosine (CAS NO.3868-31-3)


Molecular Formula: C10H13N5O6
Molecular Weight: 299.24g/mol
Mol File: 3868-31-3.mol
Melting Point: 232-235°C
Density: 2.43 g/cm3
Surface Tension: 142.6 dyne/cm
Enthalpy of Vaporization:
XLogP3-AA: -3.6
H-Bond Donor: 6
H-Bond Acceptor: 8
Structure Descriptors of 8-Hydroxyguanosine (CAS NO.3868-31-3):
  IUPAC Name: 2-amino-9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,7-dihydropurine-6,8-dione
  Canonical SMILES: C(C1C(C(C(O1)N2C3=C(C(=O)N=C(N3)N)NC2=O)O)O)O
  InChI: InChI=1S/C10H13N5O6/c11-9-13-6-3(7(19)14-9)12-10(20)15(6)8-5(18)4(17)2(1-16)21-8/h2,4-5,8,16-18H,1H2,(H,12,20)(H3,11,13,14,19) 
  InChIKey: FPGSEBKFEJEOSA-UHFFFAOYSA-N
Product Categories: Nucleotides and Nucleosides; Bases & Related Reagents; Labeling and Diagnostics Reagents; Nucleotides

8-Hydroxyguanosine Uses

 8-Hydroxyguanosine (CAS NO.3868-31-3) is a nucleoside which is an oxidative derivative of guanosine. Measurement of the levels of 8-hydroxyguanosine is used as a biomarker of oxidative stress.

8-Hydroxyguanosine Toxicity Data With Reference

1.    

sce-hmn-lym 100 nmol/L

    MUREAV    Mutation Research. 403 (1998),223.

8-Hydroxyguanosine Safety Profile

Mutation data reported. When heated to decomposition it emits toxic vapors of NOx.

8-Hydroxyguanosine Specification

 8-Hydroxyguanosine , its CAS NO. is 3868-31-3, the synonyms are 2-Amino-9-beta-D-ribofuranosylpurine-6,8(1H,9H)-dione ; 8-Oxo-2'-deoxyguanosine ; 8-Oxoguanosine ; CCRIS 8242 ; NSC 90393 ; Guanosine, 7,8-dihydro-8-oxo- (9CI) ; Purine-6,8(1H,9H)-dione, 2-amino-9-beta-D-ribofuranosyl- .

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