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8-Quinolinemethanol

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Name

8-Quinolinemethanol

EINECS N/A
CAS No. 16032-35-2 Density 1.218 g/cm3
PSA 33.12000 LogP 1.72710
Solubility N/A Melting Point 75-76℃
Formula C10H9NO Boiling Point 334.8 °C at 760 mmHg
Molecular Weight 159.188 Flash Point 156.3 °C
Transport Information N/A Appearance N/A
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 16032-35-2 (8-Quinolinemethanol) Hazard Symbols N/A
Synonyms

8-Quinolinylmethanol;

Article Data 17

8-Quinolinemethanol Specification

The 8-Quinolinemethanol, with the CAS registry number of 16032-35-2, is also known as 8-Quinolinylmethanol. This chemical's molecular formula is C10H9NO and molecular weight is 159.0. What's more, its systematic name is 8-Quinolinemethanol.

Physical properties about the 8-Quinolinemethanol are: (1)ACD/LogP: 0.90; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.87; (4)ACD/LogD (pH 7.4): 0.9; (5)ACD/BCF (pH 5.5): 2.66; (6)ACD/BCF (pH 7.4): 2.84; (7)ACD/KOC (pH 5.5): 68.83; (8)ACD/KOC (pH 7.4): 73.51; (9)#H bond acceptors: 2; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 22.12 Å2; (13)Index of Refraction: 1.667; (14)Molar Refractivity: 48.63 cm3; (15)Molar Volume: 130.5 cm3; (16)Surface Tension: 56.9 dyne/cm; (17)Density: 1.218 g/cm3; (18)Flash Point: 156.3 °C; (19)Enthalpy of Vaporization: 60.99 kJ/mol; (20)Boiling Point: 334.8 °C at 760 mmHg; (21)Vapour Pressure: 4.92E-05 mmHg at 25 °C.

Preparation: this chemical is prepared by 8-Acetoxymethylquinoline. The reaction needs reagent NaOH and solvent Methanol. The reaction time is 1.5 h. The yield is about 96 %.

The 8-Quinolinemethanol can be obtained by 8-Acetoxymethylquinoline

Uses: it is used to produce other chemicals. For example, it is used to produce (1,2,3,4-Tetrahydro-quinolin-8-yl)-methanol. This reaction needs reagent H2. Meanwhile, it needs solvent Methanol. The reaction temperature is 40 °C. The yield is about 98 %.

The 8-Quinolinemethanol can react to get (1,2,3,4-Tetrahydro-quinolin-8-yl)-methanol

You can still convert the following datas into molecular structure:
(1) SMILES: OCc1cccc2cccnc12
(2) InChI: InChI=1/C10H9NO/c12-7-9-4-1-3-8-5-2-6-11-10(8)9/h1-6,12H,7H2
(3) InChIKey: BGLZVNYGUGILJU-UHFFFAOYAM

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