- 700844-17-3Thieno[3,2-b]pyridine-6-carbonitrile,7-chloro-2-iodo-
- 700-84-55-Fluoro-1-indanone
- 70084-87-6Glutens,enzyme-modified
- 70084-97-8Silsesquioxanes, Ph, polymers with (3-aminopropyl)triethoxysilane and bisphenol A diglycidyl ether
- 7008-54-07H-Purine,6-chloro-7-[(3-nitrophenyl)methyl]-
- 70086-68-9Benzoic acid,2-chloro-, pentyl ester
- 700874-71-1LY 2109761
- 700-87-8Benzene,1-isocyanato-2-methoxy-
- 70092-45-4Cyclohexanol,2-(decyloxy)-
- 70092-46-5Cyclohexanol,2-(cyclohexyloxy)-
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
Acronycine |
EINECS | N/A |
| CAS No. | 7008-42-6 | Density | 1.208 g/cm3 |
| PSA | 40.46000 | LogP | 3.88450 |
| Solubility | 2.7mg/L(25 oC) | Melting Point |
175-176ºC |
| Formula | C20H19 N O3 | Boiling Point | 489.821ºC at 760mmHg |
| Molecular Weight | 321.376 | Flash Point | 250.035ºC |
| Transport Information | N/A | Appearance | N/A |
| Safety | Moderately toxic by ingestion and intraperitoneal routes. Questionable carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Acromycine;Acronin; Acronine; Acronycin; Acronycine; Compound 42339; NCI-C 01536; NSC 403169 |
Article Data | 18 |
Acronycine Chemical Properties
IUPAC Name: 6-methoxy-3,3,12-trimethylpyrano[2,3-c]acridin-7-one
Molecular Weight: 321.36976 g/mol
Molecular Formula: C20H19NO3
Density: 1.202 g/cm3
Boiling Point: 502.2 °C at 760 mmHg
Flash Point: 257.5 °C
Appreance: yellow powder
Water Solubility: water insoluble
Index of Refraction: 1.601
Molar Refractivity: 91.58 cm3
Molar Volume: 267.2 cm3
Polarizability: 36.3*10-24 cm3
Surface Tension: 43.4 dyne/cm
Enthalpy of Vaporization: 77.12 kJ/mol
Vapour Pressure: 3.24E-10 mmHg at 25 °C
XLogP3: 3.7
H-Bond Acceptor: 4
Rotatable Bond Count: 1
Exact Mass: 321.136493
MonoIsotopic Mass: 321.136493
Topological Polar Surface Area: 38.8
Heavy Atom Count: 24
Complexity: 543
Canonical SMILES: CC1(C=CC2=C3C(=C(C=C2O1)OC)C(=O)C4=CC=CC=C4N3C)C
InChI: InChI=1S/C20H19NO3/c1-20(2)10-9-13-15(24-20)11-16(23-4)17-18(13)21(3)14-8-6-5-7-12(14)19(17)22/h5-11H,1-4H3
InChIKey: SMPZPKRDRQOOHT-UHFFFAOYSA-N
Synonyms of Acronycine (CAS NO.7008-42-6): Acronine ; 3,12-Dihydro-6-methoxy-3,3,12-trimethyl-7H-pyrano[2,3-c]acridin-7-one ; 3,3,12-Trimethyl-6-methoxy-7,12-dihydro-3H-pyrano[2,3-c]acridine-7-one ; Compound 42339 ; NSC-403169
Acronycine Toxicity Data With Reference
| 1. | dni-mus:leu 1 µmol/L | CNREA8 Cancer Research. 33 (1973),2310. | ||
| 2. | orl-mus LD50:522 mg/kg | NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program, Bethesda, MD 20205 JAN 86 . | ||
| 3. | ipr-mus LD50:613 mg/kg | NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program, Bethesda, MD 20205 JAN 86 . | ||
| 4. | cyt-mus:fbr 10 mg/L/24H | ARZNAD Arzneimittel-Forschung. Drug Research. 27 (1977),1549. | ||
| 5. | ipr-rat TDLo:1170 mg/kg/1Y-I:CAR | NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) NCI-CG-TR-49 ,1978. | ||
| 6. | ipr-rat TD:1800 mg/kg/1Y-I:CAR | NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) NCI-CG-TR-49 ,1978. |
Acronycine Consensus Reports
NCI Carcinogenesis Bioassay (ipr); Inadequate Studies: mouse NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) NCI-CG-TR-49 ,1978. ; Clear Evidence: rat NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) NCI-CG-TR-49 ,1978.
Acronycine Safety Profile
Moderately toxic by ingestion and intraperitoneal routes. Questionable carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Acronycine Specification
Reactivity Profile Amines, like Acronycine (CAS NO.7008-42-6), are weak chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Health Hazard: When heated to decomposition Acronycine (CAS NO.7008-42-6) emits toxic fumes.
Fire Hazard: Flash point data for Acronycine (CAS NO.7008-42-6) are not available. Acronycine (CAS NO.7008-42-6 is probably combustible.
What can I do for you?
Get Best Price
