Related Products
- 39537-36-5L-Norvaline, L-alanyl-
- 39539-66-71-Piperazinecarbonylchloride, 4-methyl-
- 39539-67-83-Pyridazinamine,6-(methylthio)-
- 39540-30-2Glycine, octyl ester,hydrochloride (1:1)
- 3954-13-0Pentane, 1-isocyanato-
- 39542-83-14-Thiazolidinone,3-ethyl-5-[(phenylamino)methylene]-2-thioxo-
- 395-44-8Benzene,1-(bromomethyl)-2-(trifluoromethyl)-
- 395-45-9Benzene,1-ethenyl-2-(trifluoromethyl)-
- 39546-32-2Isonipecotamide
- 39547-15-4Phenol,2-amino-5-methoxy-, hydrochloride (1:1)
Hot Products
- 2392-39-4Pregna-1,4-diene-3,20-dione,9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, sodium salt (1:2), (11b,16a)-
- 14221-01-3Tetrakis(triphenylphosphine)palladium
- 58-27-5Menadione
- 104227-87-4Famciclovir
- 6381-92-6Disodium edetate dihydrate
- 302962-49-85-Thiazolecarboxamide,N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-
- 82410-32-0Ganciclovir
- 345-92-64,4'-Difluorobenzophenone
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
Alanyl-glutamine |
EINECS | 475-290-9 |
| CAS No. | 39537-23-0 | Density | 1.305g/cm3 |
| PSA | 135.51000 | LogP | -0.04000 |
| Solubility | Soluble in water. | Melting Point |
215 °C |
| Formula | C8H15N3O4 | Boiling Point | 615.4 °C at 760 mmHg |
| Molecular Weight | 217.225 | Flash Point | 326 °C |
| Transport Information | N/A | Appearance | N/A |
| Safety | 23-24/25-36-26 | Risk Codes | 36/37/38 |
| Molecular Structure |
|
Hazard Symbols |
 Xi
|
| Synonyms |
Glutamine,N2-L-alanyl- (7CI);L-Glutamine, N2-L-alanyl-;Dipeptamin;Dipeptiven;GlutaMAX;L-Ala-L-Gln;L-Alanyl-L-glutamine;Glutamax I; |
Article Data | 12 |
Alanyl-glutamine Synthetic route
- 39537-23-0
alanylglutamine
Conditions
| Conditions | Yield |
|---|---|
| With ammonium hydroxide at 20 - 60℃; for 8h; Autoclave; | 99.8% |
Conditions
| Conditions | Yield |
|---|---|
| Stage #1: N-Cbz-Ala With hexachloroethane; triphenylphosphine In tetrahydrofuran at 0℃; for 1.5h; Stage #2: L-glutamine With potassium hydroxide In tetrahydrofuran; dichloromethane; water at 0℃; for 2h; pH=13; Stage #3: With sulfuric acid; hydrogen Product distribution / selectivity; more than 3 stages; | 65% |
| Stage #1: N-Cbz-Ala With hexachloroethane; triphenylphosphine In toluene at 0℃; for 3h; Stage #2: L-glutamine With sodium hydroxide In water; toluene at 15℃; for 1.5h; pH=12; Stage #3: With hydrogenchloride; hydrogen Product distribution / selectivity; more than 3 stages; | 48% |
| Stage #1: N-Cbz-Ala With hexachloroethane; triphenylphosphine In acetonitrile at 5℃; for 1h; Stage #2: L-glutamine With sodium hydroxide; potassium carbonate In water; acetonitrile at 5℃; for 2h; pH=10; Stage #3: With hydrogenchloride; trifluoroacetic acid Product distribution / selectivity; more than 3 stages; | 45% |
Conditions
| Conditions | Yield |
|---|---|
| Stage #1: N-(O,O-diethyl) phosphoalanine With hexachloroethane; triphenylphosphine In dichloromethane at 0℃; for 0.666667h; Stage #2: L-glutamine With potassium hydroxide In dichloromethane; cyclohexane; water at 20℃; for 0.5h; pH=13; Stage #3: With nitric acid; trifluoroacetic acid Product distribution / selectivity; more than 3 stages; | 60% |
| Stage #1: N-(O,O-diethyl) phosphoalanine With hexachloroethane; triphenylphosphine In acetonitrile at 15℃; for 2.5h; Stage #2: L-glutamine With sodium carbonate In water; toluene; acetonitrile at 30℃; for 1h; pH=8.5; Stage #3: With sulfuric acid; hydrogen bromide Product distribution / selectivity; more than 3 stages; | 40% |
Conditions
| Conditions | Yield |
|---|---|
| Stage #1: N-pivaloylalanine With hexachloroethane; triphenylphosphine In toluene at 5℃; for 2h; Stage #2: L-glutamine With sodium hydroxide In water; toluene; Petroleum ether at 10℃; for 1.5h; pH=12; Stage #3: With hydrogenchloride; sulfuric acid Product distribution / selectivity; more than 3 stages; | 52% |
| Stage #1: N-pivaloylalanine With hexachloroethane; triphenylphosphine In tetrahydrofuran at 0℃; for 1.5h; Stage #2: L-glutamine With potassium hydroxide; sodium carbonate In tetrahydrofuran; dichloromethane; water at 8℃; for 2h; pH=10; Stage #3: With hydrogenchloride; methanesulfonic acid Product distribution / selectivity; more than 3 stages; | 45% |
| Stage #1: N-pivaloylalanine With hexachloroethane; triphenylphosphine In 1,2-dichloro-ethane at 10℃; for 0.333333h; Stage #2: L-glutamine With potassium hydroxide In cyclohexane; water; 1,2-dichloro-ethane at 20℃; for 0.5h; pH=11; Stage #3: With nitric acid; trifluoroacetic acid Product distribution / selectivity; more than 3 stages; | 40% |
Conditions
| Conditions | Yield |
|---|---|
| Stage #1: N-(O,O-diisopropyl) phosphoalanine With hexachloroethane; triphenylphosphine In 1,2-dichloro-ethane at 20℃; for 1.5h; Stage #2: L-glutamine With potassium hydroxide In water; 1,2-dichloro-ethane at 10℃; for 2h; pH=13; Stage #3: With nitric acid; trifluoroacetic acid Product distribution / selectivity; more than 3 stages; | 52% |
| Stage #1: N-(O,O-diisopropyl) phosphoalanine With hexachloroethane; triphenylphosphine In dichloromethane at 10℃; for 3h; Stage #2: L-glutamine With sodium hydroxide; sodium carbonate In dichloromethane; water; ethyl acetate at 10℃; for 1h; pH=9; Stage #3: With sulfuric acid; hydrogen bromide Product distribution / selectivity; more than 3 stages; | 45% |
Conditions
| Conditions | Yield |
|---|---|
| Stage #1: N-(O,O-dimethyl) phosphoalanine With hexachloroethane; triphenylphosphine In tetrahydrofuran at 10℃; for 0.333333h; Stage #2: L-glutamine With sodium hydroxide In tetrahydrofuran; cyclohexane; water at 25℃; for 0.5h; pH=12; Stage #3: With hydrogen bromide; nitric acid Product distribution / selectivity; more than 3 stages; | 50% |
| Stage #1: N-(O,O-dimethyl) phosphoalanine With hexachloroethane; triphenylphosphine In dichloromethane; toluene at 0℃; for 3h; Stage #2: L-glutamine With potassium hydroxide; potassium hydrogencarbonate In dichloromethane; water; toluene; Petroleum ether at 0℃; for 1.5h; pH=10; Stage #3: With hydrogenchloride; methanesulfonic acid Product distribution / selectivity; more than 3 stages; | 45% |
| Stage #1: N-(O,O-dimethyl) phosphoalanine With hexachloroethane; triphenylphosphine In toluene at 5℃; for 1h; Stage #2: L-glutamine With sodium carbonate In ethanol; water; toluene at 5℃; for 0.166667h; pH=9.5; Stage #3: With phosphoric acid; trifluoroacetic acid Product distribution / selectivity; more than 3 stages; | 40% |
- 90770-50-6
L-Alanyl-<γ-methyl>-L-glutamat
- 39537-23-0
alanylglutamine
Conditions
| Conditions | Yield |
|---|---|
| With ammonium hydroxide |
- 4652-65-7
(S)-2-Benzyloxycarbonylamino-pentanedioic acid 5-methyl ester
- 39537-23-0
alanylglutamine
Conditions
| Conditions | Yield |
|---|---|
| Multi-step reaction with 5 steps 1: Et3N / ethyl acetate / Heating 2: aq. HBr / acetic acid 3: DCC / ethyl acetate 4: H2 / Pd-C / methanol; H2O 5: aq. NH3 View Scheme |
- 96789-24-1
α-p-Nitro-benzyl-γ-methyl-L-glutamat
- 39537-23-0
alanylglutamine
Conditions
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: DCC / ethyl acetate 2: H2 / Pd-C / methanol; H2O 3: aq. NH3 View Scheme |
- N-Carbobenzoxy-<α-p-nitro-benzyl,γ-methyl>-L-glutamat
- 910908-63-3
N-Carbobenzoxy-<α-p-nitro-benzyl,γ-methyl>-L-glutamat
- 39537-23-0
alanylglutamine
Conditions
| Conditions | Yield |
|---|---|
| Multi-step reaction with 4 steps 1: aq. HBr / acetic acid 2: DCC / ethyl acetate 3: H2 / Pd-C / methanol; H2O 4: aq. NH3 View Scheme |
Alanyl-glutamine Chemical Properties
MF: C8H15N3O4
MW: 217.22
Alanyl glutamine,its melting point is 215 °C,appearance is White or off white crystalline powder .
Following is the molecular structure of Alanyl glutamine:
MW: 217.22
Alanyl glutamine,its melting point is 215 °C,appearance is White or off white crystalline powder .
Following is the molecular structure of Alanyl glutamine:
Alanyl-glutamine Uses
Alanyl glutamine can be used as Nutrient; food addiitive.
Alanyl-glutamine Safety Profile
Safty information about Alanyl glutamine:
Hazard Codes : Xi (Irritant )
Risk Statements:
R36/37/38 :Irritating to eyes, respiratory system and skin
Safety Statements :
S23:Toxic by inhalation
S24/25:Toxic in contact with skin and if swallowed
S36:Wear suitable protective clothing
S26 :In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
Hazard Codes : Xi (Irritant )
Risk Statements:
R36/37/38 :Irritating to eyes, respiratory system and skin
Safety Statements :
S23:Toxic by inhalation
S24/25:Toxic in contact with skin and if swallowed
S36:Wear suitable protective clothing
S26 :In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
Post a RFQ
1
What can I do for you?
Get Best Price
Get Best Price for 39537-23-0
L-Alanyl-L-Glutamine
