Basic information
- Name:
Betahistine mesylate
- CAS No.:
54856-23-4
- Molecular Structure:
- Formula:
- C8H12N2.2CH4O3S
- Molecular Weight:
- 328.40
- Synonyms:
- methanesulfonic acid; N-methyl-2-pyridin-2-yl-ethanamine;Prestwick_838;Betahistine mesilate;Suzutolon (TN);Suzutolon;Betahistine mesilate (JP14);Betahistine Dimesilate;2-(ethylammonio)-N-methylpyridinium dimethanesulphonate;N-METHYL-2-PYRIDINE ETHANAMINE DIMETHANESULFONATE;
- EINECS:
- 259-377-7
- Melting Point:
- 112°C
- Boiling Point:
- 210.9 °C at 760 mmHg
- Flash Point:
- 96.7 °C
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Chemistry
IUPAC Name: Methanesulfonic acid; N-methyl-2-pyridin-2-ylethanamine
Synonyms: N-Methyl-2-pyridineethanamindimethanesulfonate ; 2-[2-(Methylamino)ethyl]pyridine methanesulfonate ; Betahistine mesilate ; Betahistine mesylate ; Betahistine methanesulfonate ; Betahistine dimesylate ; Betahistine dimethanesulfonate ; N-Methyl-2-pyridineethylamine dimethanesulphonate
Molecular Structure of Betahistine mesylate (CAS NO.54856-23-4) : 
Molecular Formula-: C8H12N2.2(CH4O3S)
Molecular Weight-: 328.40
CAS NO: 54856-23-4
EINECS: 259-377-7
Melting point: 112 °C
Flash Point: 96.7 °C
Enthalpy of Vaporization: 44.72 kJ/mol
Boiling Point: 210.9 °C at 760 mmHg
Vapour Pressure: 0.187 mmHg at 25 °C
Classification Code: Drug / Therapeutic Agent
Uses
Betahistine mesylate (CAS NO.54856-23-4) is used for vertigo, dizziness and feeling, Meniere's disease, Meniere's syndrome, dizziness.
Toxicity Data With Reference
| 1. | orl-rat LD50:3030 mg/kg | NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982. 6 (1982),750. | ||
| 2. | scu-rat LD50:940 mg/kg | NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982. 6 (1982),750. | ||
| 3. | ivn-rat LD50:604 mg/kg | NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982. 6 (1982),750. | ||
| 4. | orl-mus LD50:500 mg/kg | NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982. 6 (1982),750. | ||
| 5. | scu-mus LD50:1630 mg/kg | NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982. 6 (1982),750. | ||
| 6. | ivn-mus LD50:505 mg/kg | NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982. 6 (1982),750. | ||
| 7. | orl-gpg LD50:1400 mg/kg | NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982. 6 (1982),750. | ||
| 8. | scu-gpg LD50:120 mg/kg | NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982. 6 (1982),750. | ||
| 9. | ivn-gpg LD50:22,900 µg/kg | NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982. 6 (1982),750. |
Safety Profile
Poison by subcutaneous route. Moderately toxic by ingestion and other routes. When heated to decomposition it emits toxic fumes of NOx and SOx.
RTECS: UT2970200