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Caerulein

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Name

Caerulein

EINECS N/A
CAS No. 17650-98-5 Density 1.406g/cm3
PSA 585.08000 LogP 1.81300
Solubility N/A Melting Point 224-226° (dec)
Formula C58H73 N13 O21 S2 Boiling Point °Cat760mmHg
Molecular Weight 1352.42 Flash Point °C
Transport Information N/A Appearance N/A
Safety A poison by subcutaneous route. When heated to decomposition it emits toxic vapors of NOx and SOx. Risk Codes N/A
Molecular Structure Molecular Structure of 17650-98-5 (Caerulein) Hazard Symbols A poison.
Synonyms

Caerulein1.1; Caerulein 1.1 (Litoria citropa); Cerulein; Ceruletide; FI 6934;L-Phenylalaninamide, 5-oxo-L-prolyl-L-glutaminyl-L-a-aspartyl-O-sulfo-L-tyrosyl-L-threonylglycyl-L-tryptophyl-L-methionyl-L-a-aspartyl-

 

Caerulein Chemical Properties

Chemistry informtion about Caerulein (CAS NO.17650-98-5) is:
Synonyms: [Tyr(So3h)4]Caerulein ; Pglu-Gln-Asp-Tyr[So3h]-Thr-Gly-Trp-Met-Asp-Phe-Nh2 ; Pyroglu-Gln-Asp-Tyr[So3h]-Thr-Gly-Trp-Met-Asp-Phe-Nh2 ; Pyroglu-Gln-Asp-Tyr(So3h)-Thr-Gly-Trp-Met-Asp-Phe-Nh2.2nh3 ; Pyr-Qd-Y(So3h)-Tgwmdf-Nh2 ; Pyr-Gln-Asp-Tyr(So3h)-Thr-Gly-Trp-Met-Asp-Phe-Nh2 ; Glp-Gln-Asp-Tyr(So3h)-Thr-Gly-Trp-Met-Asp-Phe-Nh2 ; Cerulein
MF: C58H73N13O21S2
MW: 1352.4 
Density: 1.464 g/cm3
Storage temp.: −20°C
Solubility: 0.05 M ammonium hydroxide: 1 mg/mL, clear, colorless
Merck: 13,2015 
Following is the molecular structure of Caerulein (CAS NO.17650-98-5) is:

Caerulein Uses

Caerulein (CAS NO.17650-98-5) is used in paralytic ileus and as diagnostic aid in pancreatic malfunction.

Caerulein Toxicity Data With Reference

1.    

scu-rat TDLo:20 µg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 293 (2000),670.
2.    

scu-rat TDLo:80 µg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 293 (2000),670.

Caerulein Safety Profile

A poison by subcutaneous route. When heated to decomposition it emits toxic vapors of NOx and SOx
WGK Germany: 3
F:
F 10: Keep under argon.
F 21: Sensitive to humidity.

Caerulein Specification

Caerulein (CAS NO.17650-98-5) is a specific decapeptide obtained from the skin of Litoria caerulea, an Australian amphibian. Caerulein is similar in action and composition to cholecystokinin. It stimulates gastric, biliary, and pancreatic secretion; and certain smooth muscle.

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