Basic information
- Name:
CARAMIPHEN ETHANE DISULFONATE
- CAS No.:
125-86-0
- Molecular Structure:
- Formula:
- C18H27NO2•1/2 C2H6O6S2
- Molecular Weight:
- 479.66
- Density:
- g/cm3
- Boiling Point:
- 392.1°Cat760mmHg
- Flash Point:
- 124.8°C
- Safety Description:
- Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of SOx and NOx. See also SULFONATES. Details
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Chemistry
Molecular Formula: C18H27NO2•1/2 C2H6O6S2
Molecular Weight: 479.66g/mol
Boiling Point: 392.1°C at 760mmHg
Melting Point: 115–116°C
Flash Point: 124.8°C
Properties: white crystalline powder
Solubility: soluble in H2O and EtOH
Freely Rotating Bonds: 8
Polar Surface Area: 29.54 Å2
Enthalpy of Vaporization: 64.18 kJ/mol
Vapour Pressure: 2.35E-06 mmHg at 25°C
The Cas Register Number of Caramiphen ethane disulfonate is 125-86-0.The chemical synonyms of Caramiphen ethane disulfonate (CAS NO.125-86-0) are Alcopon ; Taoryl ; Toryn ; Caramiphen edisilat ; Caramiphen edisylate ; Caramiphen ethanedisulfonate ; Parpanit ethane disulfonate ; Caramiphen ethane disulfonate ; Caramiphen hydrogen edisilate ; UNII-09TQU5PG95 .The molecular structure of Caramiphen ethane disulfonate (CAS NO.125-86-0) is.gif)
.
Uses
Caramiphen ethane disulfonate (CAS NO.125-86-0) is the most widely used as drug among the morphine class of compounds,and also used in a variety of pharmaceuticals including analgesics, antiperistaltics, antitussive agents, hypnotics, and sedatives. Codeine is an opioid analgesic related to morphine but with less potential analgesic property and mild sedative effect.
Toxicity Data With Reference
| 1. | orl-rat LDLo:1400 mg/kg | CLDND* Compilation of LD50 Values of New Drugs .(J.R. MacDougal,Dept. of National Health and Welfare, Food and Drug Divisions,Ottawa, Ontario, Canada.: )(1972),363. | ||
| 2. | orl-mus LD50:485 mg/kg | 27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,363. | ||
| 3. | ipr-mus LD50:240 mg/kg | 27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,363. | ||
| 4. | ivn-mus LD50:67 mg/kg | 27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,363. | ||
| 5. | ivn-rbt LD50:12 mg/kg | 27ZQAG Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,363. |
Safety Profile
Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of SOx and NOx. See also SULFONATES.