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CARBENICILLIN SODIUM (4800-94-6)

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Chemistry

Product Name: Carbenicillin sodium (CAS NO.4800-94-6)


Molecular Formula: C17H16N2Na2O6S
Molecular Weight: 422.36g/mol
Mol File: 4800-94-6.mol
Einecs: 225-360-8
Appearance: White to off-white powder
Boiling point: 737.8 °C at 760 mmHg
Storage Temperature: 2-8°C
Flash Point: 400 °C
Water Solubility: H2O: 50 mg/mL
Enthalpy of Vaporization: 112.96 kJ/mol
Vapour Pressure: 7.42E-23 mmHg at 25°C
H-Bond Donor: 1
H-Bond Acceptor: 6
Product Categories: Heterocyclic Compounds; Antibiotic Explorer

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous > 4gm/kg (4000mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969.
dog LD50 subcutaneous > 4gm/kg (4000mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969.
monkey LD50 intravenous 9800mg/kg (9800mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. Vol. 34, Pg. 405, 1975.
mouse LD50 intracrebral 95500ug/kg (95.5mg/kg)   Chemotherapy Vol. 17, Pg. 1111, 1969.
mouse LD50 intraperitoneal 7600mg/kg (7600mg/kg)   Drugs in Japan Vol. 6, Pg. 187, 1982.
mouse LD50 intravenous 4500mg/kg (4500mg/kg)   Chemotherapy Vol. 23, Pg. 572, 1975.
mouse LD50 oral > 12gm/kg (12000mg/kg)   Chemotherapy Vol. 23, Pg. 572, 1975.
mouse LD50 subcutaneous 9gm/kg (9000mg/kg)   Drugs in Japan Vol. 6, Pg. 187, 1982.
rabbit LD50 intravenous > 4gm/kg (4000mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969.
rabbit LD50 subcutaneous > 4gm/kg (4000mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969.
rat LD50 intraperitoneal 10gm/kg (10000mg/kg)   Drugs in Japan Vol. 6, Pg. 187, 1982.
rat LD50 intravenous 6800mg/kg (6800mg/kg)   Drugs in Japan Vol. 6, Pg. 187, 1982.
rat LD50 oral > 10gm/kg (10000mg/kg)   Drugs in Japan Vol. 6, Pg. 187, 1982.
rat LD50 subcutaneous > 10gm/kg (10000mg/kg)   Drugs in Japan Vol. 6, Pg. 187, 1982.

Safety Profile

Mildly toxic by subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of NOx, Na2O, and SOx. See also CARBENICILLIN PHENYL SODIUM.
Safety Information of Carbenicillin sodium (CAS NO.4800-94-6):
Hazard Codes: Xn
Risk Statements: 42/43
42:  May cause sensitization by inhalation 
43:  May cause sensitization by skin contact
Safety Statements: 22-36/37-36
22:  Do not breathe dust
36:  Wear suitable protective clothing  
37:  Wear suitable gloves 

Specification

 Carbenicillin sodium ,its CAS NO. is 4800-94-6,the synonyms is Brl-2064 ; Carbecin ; Carboxybenzylpenicillinsodium ; Cp-15-639-2 ; Disodiumcarbenicillin ; Fugacillin ; Geopen ; Gripenin .

Basic information

  • Product Name:

    CARBENICILLIN SODIUM

  • CAS No:4800-94-6
  • Formula:C17H18 N2 O6 S . 2 Na
  • Synonyms:4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(carboxyphenylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt,(2S,5R,6R)- (9CI); 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[(carboxyphenylacetyl)amino]-3,3-dimethyl-7-oxo-, disodium salt, [2S-(2a,5a,6b)]-; Malonamic acid,N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl)-2-phenyl-,disodium salt (7CI,8CI); Anabactyl; BRL 2064; CP 15639-2; Carbapen; Carbecin;Carbenicillin disodium; Carbenicillin disodium salt; Carbenicillin sodium;Carbenicilline disodium; Carboxybenzylpenicillin sodium; Disodium (a-carboxybenzyl)penicillin;Disodium carbenicillin; Fugacillin; Geocillin; Geopen; Gripenin; Hyoper;Microcillin; NSC 111071; Piopen; Pyopen; Pyopene; Sodium carbenicillin; a-Carboxybenzylpenicillin disodiumsalt; a-Carboxybenzylpenicillin sodiumsalt
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