- APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS AND USES THEREOF
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Described herein are ASK1 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of blood disease, autoimmune disorders, pulmonary disorders, hypertension, inflammatory diseases, fibrotic diseases, diabetes, diabetic nephropathy, renal diseases, respiratory diseases, cardiovascular diseases, acute lung injuries, acute or chronic liver diseases, and neurodegenerative diseases.
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Paragraph 00651; 00590
(2019/04/09)
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- BICYCLIC PYRROLE DERIVATIVES USEFUL AS AGONISTS OF GPR120
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The present invention is directed to bicyclic pyrrole derivatives of formula (I), pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by GPR120. More particularly, the compounds of the present invention are agonists of GPR120, useful in the treatment of, such as for example. Type II diabetes mellitus.
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Page/Page column 90; 91
(2015/09/28)
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- BICYCLIC PYRROLE DERIVATIVES USEFUL AS AGONISTS OF GPR120
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The present invention is directed to bicyclic pyrrole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by GPR120. More particularly, the compounds of the present invention are agonists of GPR120, useful in the treatment of, such as for example, Type II diabetes mellitus.
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Paragraph 0374; 0376
(2014/09/30)
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- Bicyclic pyrrole derivatives useful as agonists of GPR120
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The present invention is directed to bicyclic pyrrole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by GPR120. More particularly, the compounds of the present invention are agonists of GPR120, useful in the treatment of, such as for example, Type II diabetes mellitus.
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Page/Page column 74-75
(2015/01/06)
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