- HETEROARYL COMPOUNDS AND USES THEREOF
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Described herein are compounds of formula (I), and pharmaceutically acceptable salts, solvates, hydrates, isotopically labeled derivatives and radiolabeled derivative thereof, and pharmaceutical compositions thereof. Also provided are methods and kits involving the inventive compounds or compositions for detecting and imaging Tau aggregates in the brain for detection of Alzheimer's disease (AD) in a subject.
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Paragraph 0116-0118
(2019/11/28)
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- SUBSTITUTED PYRIDOPYRAZINES AS NOVEL SYK INHIBITORS
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Provided are pyridopyrazine compounds of formula (1), pharmaceutical compositions thereof and methods of use therefore, wherein R1, R2, R3, R4 and m are as defined in the specification.
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Paragraph 0160; 0161
(2014/05/08)
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- SUBSTITUTED PYRIDOPYRAZINES AS NOVEL SYK INHIBITORS
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Provided are certain pyridopyrazine compounds, pharmaceutical compositions thereof and methods of use therefor.
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Page/Page column 35
(2013/02/27)
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- PYRAZOLE COMPOUNDS
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The present invention is directed to compounds of Formula (I) and to pharmaceutically acceptable salts thereof, their synthesis, and their use as Raf inhibitors.
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Page/Page column 62-63
(2009/03/07)
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- 2,4-SUBSTITUTED QUINAZOLINES AS LIPID KINASE INHIBITORS
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The invention relates to compounds of the formula (I), which are appropriate for the treatment of kinase, e.g. PI3K-related, diseases, such as proliferative diseases, inflammatory diseases, obstructive airways disorders and transplantation related disease
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Page/Page column 70
(2008/06/13)
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- NOVEL HETEROARYL SUBSTITUTED BENZOTHIAZOLES
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The present invention relates to novel heteroaryl substituted benzothiazole derivatives, precursors thereof, and therapeutic uses for such compounds, having the structural formula (I) below: [Chemical formula should be inserted here. Please see paper copy
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Page/Page column 92-93
(2008/06/13)
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