METABOTROPIC GLUTAMATE RECEPTOR NEGATIVE ALLOSTERIC MODULATORS (NAMS) AND USES THEREOF
Provided herein are small molecule active metabotropic glutamate subtype-2 and -3 receptor negative allosteric modulators (NAMs), compositions comprising the compounds, and methods of using the compounds and compositions.
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Paragraph 00332
(2016/01/01)
Facile synthesis of substituted 5-amino- And 3-amino-1,2,4-thiadiazoles from a common precursor
[Chemical Equation Presented] A novel approach to the synthesis of substituted 5-amino- and 3-amino-1,2,4-thiadiazoles beginning from a common precursor has been achieved. Derivatization by palladium-catalyzed Suzuki-Miyaura coupling enables the rapid pre
Wehn, Paul M.,Harrington, Paul E.,Eksterowicz, John E.
supporting information; experimental part
p. 5666 - 5669
(2010/03/01)
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