cas 101973-77-7, 2-acetylthiomethyl-3-(4-methylbenzoyl)propionic acid | Articles data ｜lookchem

Welcome to LookChem.com Sign In|Join Free

Article Database

Home > CAS Article list >
101973-77-7

Articles about 101973-77-7Total 4 be found

Article title
Article abstract
Author
Journal number and time
Download

Functional activity of the mouse flavin-containing monooxygenase forms 1, 3, and 5
Three functional mouse flavin-containing monooxygenases (mFMOs) (i.e., mFMO1, mFMO3, and mFMO5) have been reported to be the major FMOs present in mouse liver. To examine the biochemical features of these enzymes, recombinant enzymes were expressed as mal
Zhang, Jun,Cerny, Matt A.,Lawson, Matt,Mosadeghi, Ruzbeh,Cashman, John R.
p. 206 - 215
(2007)
Read Online

A practical procedure for the synthesis of Esonarimod, (R,S)-2-acetylthiomethyl-4-(4-methylphenyl)-4-oxobutanoic acid, an antirheumatic agent. II
An efficient large-scale synthesis of Esonarimod, (R,S)-2-acetylthio-methyl-4-(4-methylphenyl)-4-oxobutanoic acid (1), a new antirheumatic drug, was established. A small amount of water increased the yield of the Michael addition of thioacetic acid (4) to
Noguchi, Toshiya,Onodera, Akira,Ito, Masato,Yoshida, Mamoru,Yokomori, Sadakazu
p. 2657 - 2670
(2003)
Read Online

A practical procedure for the synthesis of esonarimod, (R,S)-2-acetylthiomethyl-4-(4-methylphenyl)-4-oxobutanoic acid, an antirheumatic agent (part 1).
An efficient and practical procedure for the synthesis of esonarimod, (R,S)-2-acetylthiomethyl-4-(4-methylphenyl)-4-oxobutanoic acid (1), a new antirheumatic drug, has been developed. The intermediate, 2-methylene-4-(4-methylphenyl)-4-oxobutanoic acid (2), was prepared by Friedel-Crafts acylation of toluene with itaconic anhydride (3) in the presence of aluminum trichloride and nitrobenzene in 63% yield without silica gel column purification. Compound 1 was prepared by Michael addition of 2 with thioacetic acid (4) in 74% yield. Overall, 1 was obtained in 47% yield from 3. The structures and synthetic mechanisms of by-products (five compounds) of 2 were also clarified.
Noguchi, Toshiya,Onodera, Akira,Tomisawa, Kazuyuki,Yokomori, Sadakazu
p. 1407 - 1412
(2007/10/03)

Studies on antirheumatic agents: 3-benzoylpropionic acid derivatives
-
Kameo,Ogawa,Takeshita,Nakaike,Tomisawa,Sota
p. 2050 - 2060
(2007/10/02)

More Articles about upstream products of 101973-77-7

More Articles about downstream products of 101973-77-7

Chemical Properties

Boiling Point: 477.7°Cat760mmHg
Flash Point:242.7°C
Density: 1.241g/cm³
Storage Temp.:2-8°C
Vapor Pressure: 6.18E-10mmHg at 25°C
PSA: 96.74000
LogP: 2.54830

Show more

Global suppliers and manufacturers of 101973-77-7total 8 suppliers on LookChem

Company Name
Business Type
Min Order
FOB Price
Main Products
Contact

SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Business Type:Lab/Research institutions
Min Order:4 Kilogram
FOB Price:No Data
Main Products:35
Country:

ZHEJIANG JIUZHOU CHEM CO.,LTD
Business Type:Trading Company
Min Order:1 Kilogram
FOB Price:No Data
Main Products:27
Country:

BOC Sciences
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:41
Country:

Shanghai Yuanye Bio-Technology Co., Ltd.
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:31
Country:

Wuhan Sun-shine Bio-technology Corporation Limited
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

tianjin kailiqi biotechnology co.，ltd
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Wuhan MoonZY Biological Technology Co.,Ltd
Business Type:Lab/Research institutions
Min Order:100 Milligram
FOB Price:No Data
Main Products:1
Country:

Beijing Jin Ming Biotechnology Co., Ltd.
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 101973-77-7

About us - Payment - Contact us - Links - Help Center - Disclaimer
SiteMap | Manufacturers | VIP Product | Suppliers | CAS | New CAS | Cas Database | Article Data | Chemical Catalog | Product Name

©2008 LookChem.com,License:ICP NO.:Zhejiang16009103 complaints:service@lookchem.com
[Hangzhou]86-571-87562588,87562561,87562573 Our Legal adviser: Lawyer