Cerium(IV) sulfate catalyzed one-pot threecomponent diastereo selective synthesis of 4-amidotetrahydropyrans
A convenient and diastereoselective one-pot synthesis of cis-4-amidotetrahydropyrans is described. This simple protocol involves Prins cyclization of homoallylic alcohol and aldehydes, followed by Ritter reaction of acetonitrile leading to the formation o
Iodine/accl-catalyzed prins-ritter reaction: Synthesis of 4-amido tetrahydropyrans
Homoallylic alcohols, carbonyl compounds and nitriles undergo a smooth tandem Prins-Ritter type cyclization in the presence of iodine/AcCl at room temperature to produce 4-acetamido tetrahydropyrans in high yields with all cis-selectivity.
Srinivasan,Perumal,Raja
experimental part
p. 1083 - 1091
(2011/10/01)
Bismuth-triflate-catalyzed Prins-Ritter reaction - An efficient synthesis of 4-amidotetrahydropyrans
Bismuth(III) triflate is found to be an effective Lewis acid in catalyzing a three-component reaction of homoallylic alcohol, carbonyl compound, and nitrile at ambient temperature via the Prins-Ritter sequence to furnish 4-amidotetrahydropyrans in high yi
Yadav,Subba Reddy,Chaya,Narayana Kumar
p. 769 - 773
(2008/12/20)
Three-component, one-pot diastereoselective synthesis of 4-amidotetrahydropyrans via the Prins-Ritter reaction sequence
Three-component coupling of carbonyl compounds, homoallylic alcohols, and nitriles has been achieved using 20 mol % of phosphomolybdic acid (PMA) at ambient temperature via the Prins-Ritter sequence to furnish 4-amidotetrahydropyrans in high yields with a