- SUBSTITUTED PIPERAZINE COMPOUNDS AND METHODS AND USE THEREOF
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Provided herein are novel piperazine compounds acting as selective serotonin reuptake inhibitors and/or the 5-HT1A receptor agonists. The invention also relates to the methods of preparing the compound and pharmaceutical composition, and the use of treating central nervous system dysfunction in mammals especially in humans.
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Paragraph 00239; 00362
(2015/11/27)
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- Synthesis and antitumor activity of ureas containing pyrimidinyl group
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A novel series of ureas containing pyrimidinyl group were designed and synthesized. Some of the prepared compounds showed potential cytotoxicity against several human cancer cell lines. From the structure-activity relationships we may conclude that introd
- Jin, Chuanfei,Liang, Yong-Ju,He, Hongwu,Fu, Liwu
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experimental part
p. 429 - 432
(2011/02/25)
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- Acylaminoaryloxy and arylthio pyrimidines as herbicides
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As new compounds, acylaminoaryloxy and arylthio pyrimidines having the formula STR1 wherein A is oxygen or sulfur; M is CH or N; X is hydrogen, lower alkyl, halo, methoxy, alkoxy, C1 -C3 alkylthio, cyano, carbomethoxy or trifluoromet
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