- Synthesis and biological characterization of 99mTc(I) tricarbonyl cysteine complex, a potential diagnostic for assessment of renal function
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Cysteine containing three functional groups, i.e. a carboxyl, sulfhydryl, and amino group, has been labelled with 99mTc(I) tricarbonyl precursor (2) in order to study the renal characteristics of the resulting 99mTc(I) tricarbonyl cy
- Park, Sang Hyun,Jang, Beom Su,Park, Kyung Bae
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- METHOD FOR PREPARING S-Bz-MAG3 AS A PRECURSOR OF CONTRAST MEDIA
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The present invention provides a method for preparing S-Bz-MAG3 as a precursor of contrast media. Thioglycolic acid and benzoyl chloride are taken for the thiol protection reaction. Next, N,N′-dicyclohexylcarbodiimide and N-hydroxysuccinimide are converte
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- COMPOSITIONS AND ASSOCIATED METHODS FOR RADIOISOTOPE-BINDING MICROPARTICLES
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The present disclosure relates to polymeric materials that may be labeled with a radioisotope, to processes for producing the labeled polymeric material, and to methods of using the materials in analytical and therapeutic applications. Specifically, the disclosure relates to injectable and implantable microparticles, such as microspheres, which are associated with radioisotopes such that the microparticles are both therapeutic and detectable. The radioisotope-containing microparticles are useful for embolization and other therapeutic medical applications.
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- A novel d-glucose derivative radiolabeled with technetium-99m: Synthesis, biodistribution studies and scintigraphic images in an experimental model of Ehrlich tumor
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A d-glucose-MAG3 derivative was successfully synthesized and radiolabeled in high labeling yield. Biodistribution studies and scintigraphic images in Ehrlich tumor-bearing mice were performed. This compound showed high accumulation in tumor tis
- de Barros, André Luís Branco,Cardoso, Valbert Nascimento,Mota, Luciene das Gra?as,Leite, Elaine Amaral,de Oliveira, M?nica Cristina,Alves, Ricardo José
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scheme or table
p. 2478 - 2480
(2010/07/06)
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- Synthesis and biological evaluation of technetium-labeled d-glucose-MAG3 derivative as agent for tumor diagnosis
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A d-glucose-MAG3 derivative was successfully synthesized and radiolabeled in high labeling yield. Biodistribution studies in Ehrlich tumor-bearing mice were performed. This compound showed high accumulation in tumor tissue with high tumor-to-muscle ratio and moderate tumor-to-blood ratio. Thus, d-glucose-MAG3 is a potential agent for tumor diagnosis.
- de Barros, Andre Luis Branco,Cardoso, Valbert Nascimento,Mota, Luciene das Gracas,Leite, Elaine Amaral,Oliveira, Monica Cristina de,Alves, Ricardo Jose
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scheme or table
p. 2497 - 2499
(2009/12/25)
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