- Substituted Disulfonamide Compounds
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Substituted disulfonamide compounds corresponding to formula I: In which R1, R2, R3, R4a, R4b, R5a, R5b, R8, R9a, R9b, R10, R11, a, b, s, t and A have defined meanings, pharmaceutical compositions containing one or more such compounds, processes for preparing such compounds, and a method of using such compounds for the treatment or inhibition of pain and/or other conditions mediated by the bradykinin receptor 1 (BR1).
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Page/Page column 48
(2010/06/22)
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- A practical and efficient preparation of the releasable naphthosultam side chain of a novel anti-MRSA carbapenem
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A practical large-scale synthesis of the naphthosultam-based side chain of the anti-MRSA antibiotic 1 has been achieved in 29% overall yield over seven steps from 1-methylnaphthalene. The synthesis was completed without the use of protecting groups, featu
- Miller, Ross A.,Humphrey, Guy R.,Lieberman, David R.,Ceglia, Scott S.,Kennedy, Derek J.,Grabowski, Edward J. J.,Reider, Paul J.
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p. 1399 - 1406
(2007/10/03)
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