Synthesis of pyrazolo[3,4-b]pyridines using ammonium acetate as green reagent in multi-component reactions
(Chemical Equation Presented) Several new pyrazolo[3,4-b]pyridine derivatives were synthesized by one pot cyclocondensation of the components; 5-amino-3-aryl-1H-phenylpyrazoles, p-substituted benzoylacetonitriles and some aldehydes. The condensations were most effective by using ammonium acetate as the base catalyst; triethylamine was also studied as a catalyst.
Get Best Price for1053237-96-93-(4-chlorophenyl)-6-(4-methylphenyl)-4-[3-(4-chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile