- Ligand-promoted ortho-C-H amination with Pd catalysts
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2,4,6-Trimethoxypyridine is identified as an efficient ligand for promoting a Pd-catalyzed ortho-C-H amination of both benzamides and triflyl-protected benzylamines. This finding provides guidance for the development of ligands that can improve or enable PdII-catalyzed Csp2-H activation reactions directed by weakly coordinating functional groups.
- Zhu, Dajian,Yang, Guoqiang,He, Jian,Chu, Ling,Chen, Gang,Gong, Wei,Chen, Ke,Eastgate, Martin D.,Yu, Jin-Quan
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supporting information
p. 2497 - 2500
(2015/02/19)
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- Novel Annelation Method to Pyridine and Isoquinoline by Photochemical Means
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Intramolecular photoaddition reactions of 2-(ω-alkenyl)isoquinolin-1(2H)-ones and 1-(ω-alkenyl)pyridin-2(1H)-ones were examined, and the regioselectivity and dependence of these reactions on the length of methylene chain in the alkenyl group were clarified.By utilizing these reactions, a synthetic route to indolizine and quinolizine derivates was elaborated.By an extension of this approach to the intermolecular reaction, 6-methoxy-3-methyl-1,2-dihydrocyclobutapyridin-4(3H)-one was synthesized from 4,6-dimethoxy-1-methylpyridin-2(1H)-one.Keywords-2+2 photocycloaddition; intramolecular photoaddition; photocycloreversion; annelation; indolizine; quinolizine; cyclobutapyridine; 4,6-dimethoxypyridin-2(1H)-one; 1-(ω-alkenyl)pyridin-2(1H)-one; 2-(ω-alkenyl)isoquinolin-1(2H)-one
- Kaneko, Chikara,Uchiyama, Keiji,Sato, Masayuki,Katagiri, Nobuya
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p. 3658 - 3671
(2007/10/02)
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