A new approach to the synthesis of podophyllotoxin based on epimerization reactions
A formal synthesis of podophyllotoxin has been achieved by means of the well known conjugate addition-alkylation of 5H-furan-2-one, followed by cyclization and controlled epimerizations. This approach represents a useful new route to the 8,7'-trans-stereo
Medarde, Manuel,Ramos, Angel C.,Caballero, Esther,Lopez, Jose Luis,Pelaez-Lamamie De Clairac, Rafael,San Feliciano, Arturo
p. 2663 - 2666
(2007/10/03)
SYNTHESIS OF NEW ARYLTETRALIN LIGNANS
Cyclization with CF3CO2H of the dibenzyllactone compounds 3 and 4 afforded the aryltetralin derivatives 6a and 6b, epimers at the carbon α to the lactonic carbonyl group, in which the aryl substituent group is in the α-axial position. 1H NMR data assignme
Gonzalez, Antonio G.,Rosa, Rafael de la,Trujillo, Juan M.
p. 3899 - 3904
(2007/10/02)
More Articles about upstream products of 108440-56-8