- Synthesis of dl-standishinal and its related compounds for the studies on structure-activity relationship of inhibitory activity against aromatase
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dl-Standishinal (1), an aromatase inhibitor isolated from Thuja standishii, was synthesized in 15 steps from p-formylanisole via aldol reaction of 12-hydroxy-6,7-secoabieta-8,11,13-trien-6,7-dial (2). In the present study, we found that the aldol condensa
- Katoh, Takahiro,Akagi, Taichi,Noguchi, Chie,Kajimoto, Tetsuya,Node, Manabu,Tanaka, Reiko,Nishizawa (nee Iwamoto), Manabu,Ohtsu, Hironori,Suzuki, Noriyuki,Saito, Koichi
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- Diterpene Synthesis. Part 2. Acid-catalysed Cyclisation of p-Methoxyphenylethyltrimethylcyclohexanols
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The acid-catalysed reactions of two phenylethylcyclohexanols, precursors to tricyclic diterpenoids, are reported.The reaction produced both a bicyclic alkene and a tricyclic molecule; the former was converted into the latter in protic media.Conditions for
- Axon, Barry W.,Davis, Brian R.,Woodgate, Paul D.
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p. 2956 - 2962
(2007/10/02)
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