- Glycerol derivatives, their production and use
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Compounds of the formula: STR1 wherein R1 is a higher alkyl group which may be substituted; R2 is a hydrogen, a lower alkyl group which may be substituted, a lower alkanoyl group which may be substituted or a lower alkylthiocarbamoyl group; R3 is a primary to tertiary amino group or a quaternary ammonium group; and n is 2 or 3, and salts thereof, have antitumor activity and platelet activating factor inhibitory activity.
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- Phospholipid derivatives
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Phospholipid derivatives of the formula: STR1 wherein R1 is a higher alkyl, acylmethyl or alkylcarbamoyl group which may be substituted by cycloalkyl; R2 is a lower alkyl which may be substituted by carboxy, formyl or lower acyl, a carbamoyl or thiocarbamoyl group which is substituted by lower alkyl, or an acetoacetyl group; R3, R4 and R5 are independently hydrogen or lower alkyl, or STR2 represents a cyclic ammonio group; and n represents an integer of 8 to 14, and salts thereof have antitumor activity.
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