cas 111885-17-7, 2,3-dimethoxy-5-methyl-6-(4-oxo-1-phenyl-4-thiomorpholin-4-ylbutyl)cyclohexa-2,5-diene-1,4-dione

Articles about 111885-17-7Total 2 be found

Preparation and pharmacological evaluation of 4-(1,4-benzoquinon-2-yl)-4-phenylbutanamides as potential cerebral protective agents
A new series of 4-(1,4-benzoquinon-2-yl)-4-phenylbutanamides (2) were synthesized for evaluation of their pharmacological activities. All these compounds synthesized showed significant antilipidperoxidation (ALP) activities with brain homogenate in rats and some of them possessed a protective effect against hypobaric hypoxia in mice. Especially, a thiomorpholine derivative (21, SUN-4757) showed a wide efficacy spectrum to a variety of experimental screening assays designed for cerebral protective agents, and it had a high LD50 value.
Tatsuoka,Suzuki,Imao,Satoh,Ishihara,Hirotsu,Kihara,Hatta,Horikawa,Sumoto,Miyano
p. 2382 - 2386
(2007/10/02)

Derivative of benzoquinonylphenyl alkanoic acid amide
A derivative of benzoquinonylphenyl alkanoic acid amide having the formula: STR1 wherein X represents an oxygen atom, sulfur atom, or methylated nitrogen atom, Me represents methyl, and n is 2 or 3. This derivative is effective as a cerebral insufficiency
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(2008/06/13)