- Potential Antimalarials. XXI Mannich Base Derivatives of 4-phenols
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Syntheses are reported for 4-(7-chloroquinolin-4-ylamino)-2,6-bis(piperidin-1-ylmethyl)phenol (2) and its 3-fluoro and 3-piperidinyl derivatives.Some mono-Mannich analogues with 2-fluoro, 2-t-butyl and 3-trifluoromethyl substituents have also been prepare
- Barlin, Gordon B.,Ireland, Stephen J.,Nguyen, Trang M. T.,Kotecka, Barbara,Rieckmann, Karl H.
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p. 1553 - 1560
(2007/10/02)
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- Potential Antimalarials. VII. Di-Mannich Bases of 4-aminophenol via 4-Nitrophenols
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A series of di-Mannich bases have been prepared from 4-nitrophenol and paraformaldehyde with dimethylamine, diethylamine, dipropylamine, N-(2'-hydroxyethyl)methylamine, piperidine, 3- and 4-methylpiperidine, 3,5-dimethylpiperidine or pyrrolidine.These nit
- Barlin, Gordon B.,Ireland, Stephen J.
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p. 1727 - 1734
(2007/10/02)
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