An expeditious, solvent-free synthesis of some 5-aryl-2-(2-hydroxyphenyl)- 1,3,4-oxadiazoles
An efficient, rapid, microwave-accelerated one-step synthesis of some 5-aryl-2-(2-hydroxy-phenyl)-1,3,4-oxadiazoles by reaction of salicylic hydrazide with carboxylic acids in the presence of thionyl chloride under neat conditions is described.
Saeed, Aamer
p. 1072 - 1075
(2008/09/18)
Studies on Thioamides and Their Derivatives,VI. New Synthesis of 5-Membered Heterocyclic Compounds
Simple N-monosubstituted thioamides react with acid hydrazides to form 1,2,4-triazole derivatives.N,N-Disubstituted thioamides alkylated with methyl iodide readily yield with acid hydrazides 1,3,4-oxadiazoles.
Santus, Maria
p. 179 - 182
(2007/10/02)
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