The Application of N-Substituted Trichloroacetamides as in situ Isocyanate Generating Reagents for the Synthesis of Acylureas and Sulfonylureas
In dimethylsulfoxide solution in the presence of excess of powdered sodium hydroxide, N-substituted trichloroacetamides 1 are used as in situ isocyanate generating reagents which can react with carboxamides or sulfonamides 2 to afford acylureas or sulfonylureas 3.
Atanassova, Ivanka A.,Petrov, Jan S.,Mollov, Nikola M.
p. 734 - 736
(2007/10/02)
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