- SYNTHESIS OF 4-SUBSTITUTED 1-METHYL(BENZYL)-2,5-DIMETHYL-4-R-AMINOPIPERIDINES
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Schiff base derivatives of 1-methyl(benzyl)-2,5-dimethylpiperidin-4-ones with phenyl, α-pyridyl, benzyl, and β-hydroxyethyl substituents attached to the imine nitrogen atom react with organometallic compounds to give analogously substituted piperidine bases with methyl, allyl, phenyl, and benzyl substituents in the the 4-position.Pure individual geometric isomers of these newly synthetised compound have been isolated and their structures determined.
- Kuznetsov, V. V.,Gaivoronskaya, L. A.,Romero, R. M.,Stashenko, E. E.,Zakharov, P. I.,Prostatkov, N. S.
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p. 783 - 786
(2007/10/02)
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