Straightforward Access to a Great Diversity of Complex Biorelevant γ-Lactams Thanks to a Tunable Cascade Multicomponent Process
This reviews surveys the preparation of a great diversity of complex biorelevant γ-lactam backbones thanks to scalable copper(I)-catalyzed cascade multicomponent processes.
Mardjan, Muhammad Idham Darussalam,Mayooufi, Atef,Parrain, Jean-Luc,Thibonnet, Jér?me,Commeiras, Laurent
Efficient Regio- And Stereoselective Synthesis of 5-Alkyl(aryl)idene- and 5-[Iodoalkyl(aryl)idene]-1H-pyrrol-2(5//)-ones via Electrophilic Cyclization
A variety of substituted 5-alkyl(aryl)idene-and 5-[1o-doalkyl(aryl)idene]- 1ff-pyrrol-2(5H)-ones were readily prepared with good yields under very mild reaction conditions by the iodocy- clization of (2Z,4E)-dienamides and (Z)-alk-2-en-4-ynamides with iod