Use of tetrahydro-2H-1,3-oxazinones as aminopropylation agents
Treatment of tetrahydro-2H-1,3-oxazin-2-one (1) or the 3-methyl derivative 2 with aniline salts or thiophenols at 180°C affords the corresponding N-aryl-1,3-propanediamines 3 or 3-(arylthio)propanamines 4 in good yields.
Poindexter,Strauss
p. 1329 - 1338
(2007/10/02)
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