cas 114873-04-0, BOC-D-2,4-DICHLOROPHENYLALANINE

The discovery and optimization of a series of pyrrolopyrimidine based protein kinase B (Pkb/Akt) inhibitors discovered via HTS and structure based drug design is reported. The compounds demonstrate potent inhibition of all three Akt isoforms and knockdown of phospho-PRAS40 levels in LNCaP cells and tumor xenografts.

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Zhuozhou Wenxi import and Export Co., Ltd
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Ality Chemical Corporation
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Article Database

114873-04-0

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Chemical Properties

Appearance/Colour :white powder

Melting Point: 133-137 °C

Boiling Point: 476.1 °C at 760 mmHg

Flash Point:241.8 °C

Density: 1.323 g/cm³

Storage Temp.:2-8°C

Vapor Pressure: 7.13E-10mmHg at 25°C

PKA: 3.78±0.12(Predicted)

PSA: 75.63000

LogP: 3.90470

Global suppliers and manufacturers of 114873-04-0total 47 suppliers on LookChem

Article Database

114873-04-0

Articles about 114873-04-0Total 1 be found

More Articles about upstream products of 114873-04-0

More Articles about downstream products of 114873-04-0

Chemical Properties

Appearance/Colour :white powder

Melting Point: 133-137 °C

Boiling Point: 476.1 °C at 760 mmHg

Flash Point:241.8 °C

Density: 1.323 g/cm3

Storage Temp.:2-8°C

Vapor Pressure: 7.13E-10mmHg at 25°C

PKA: 3.78±0.12(Predicted)

PSA: 75.63000

LogP: 3.90470

Global suppliers and manufacturers of 114873-04-0total 47 suppliers on LookChem

Density: 1.323 g/cm³