Provided herein are compounds and methods for inhibiting histone deacetylase ("HDAC") enzymes (e.g., HDAC1, HDAC2, and HDAC3).
-
(2018/07/29)
One-pot synthesis of gem-difluorostyrenes from benzyl bromide via olefination of phosphonium ylide with difluorocarbene
A new approach for the synthesis of gem-difluorostyrenes from benzyl bromide is described. Quaternization of triphenylphosphine with benzyl bromide to give phosphonium salts, deprotonation of the corresponding phosphonium salts to produce phosphonium ylide, and the subsequent olefination of phosphonium ylide with difluorocarbene generated from difluoromethylene phosphobetaine (Ph3P+CF2CO2-) by decarboxylation can occur smoothly in one-pot, furnishing the final gem-difluorostyrenes in good yields.
Deng, Xiao-Yun,Lin, Jin-Hong,Xiao, Ji-Chang
p. 116 - 120
(2015/11/10)
Novel C18 modified retrosteroids as progesterone receptor modulator compounds
Retrosteroidal compounds of formula I which act as progesterone receptor modulators, a method for their production, and pharmaceutical preparations containing these compounds. These compounds are preferably used for the treatment of benign gynecological disorders such as endometriosis and uterine fibroids, as well as for female birth control and for hormone replacement therapy (HRT).
-
Page/Page column 41
(2008/06/13)
REACTIONS OF PHOSPHORUS YLIDES WITH ACYLATING AGENTS IN A TWO-PHASE SYSTEM
-
Listvan, V. N.,Stasyuk, A. P.,Kurgan, L. N.
p. 1366 - 1371
(2007/10/02)
More Articles about upstream products of 115032-61-6