- QUATERNARY AMMONIUM SALT COMPOUNDS
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[Problem] The object of the present invention is to provide a novel compound having 132 adrenergic receptor agonist activity and muscarinic receptor antagonist activity. [Means for Solving the Problem] The present invention is a quaternary ammonium salt compounds represented by formula (I), or a pharmaceutically acceptable salt thereof, with superior β32 adrenergic receptor agonist activity and muscarinic receptor antagonist activity.
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Page/Page column 41
(2012/03/10)
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- CCR10 ANTAGONISTS
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The invention relates to a compound of formula (I) or a tautomer thereof or a pharmaceutically acceptable salt thereof, wherein R1 to R11, W, X, Y, Z, and n are as defined herein. The invention also relates to methods of using the compounds of formula (I) and compositions thereof to treat various diseases and disorders in a patient. The invention also relates to processes for preparing the compounds of formula (I) and intermediates useful in these processes.
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Page/Page column 79
(2009/05/28)
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- SELECTIVE REDUCTION OF AROMATIC / ALIPHATIC NITRO GROUPS BY SODIUM SULFIDE.
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Sodium sulfide can be used to reduce selectively aromatic / aliphatic nitro groups.In the absence of water, the aromatic nitro group can be reduced selectively in the presence of a secondary aliphatic one.However, in the presence of a tertiary aliphatic n
- Huber, Didier,Andermann, Guy,Lecrerc, Gerard
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p. 635 - 638
(2007/10/02)
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