cas 116817-84-6, S-(+)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamide | Articles data ｜lookchem

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116817-84-6

Articles about 116817-84-6Total 3 be found

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Pyridino-pyrimidine compound and application thereof
The invention relates to a compound as shown in formula I, enantiomer, raceme or salt thereof, and application of the compound in tumor treatment.
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Paragraph 0247; 0248; 0252; 0253

(2019/05/28)

Duloxetine (Cymbalta), a dual inhibitor of serotonin and norepinephrine reuptake.
A series of naphthalenyloxy-arylpropylamines have been prepared and are demonstrated to be inhibitors of both serotonin and norepinephrine reuptake. One member of this series, duloxetine (Cymbalta) has proven to be effective in clinical trials for the treatment of depression.
Bymaster,Beedle,Findlay,Gallagher,Krushinski,Mitchell,Robertson,Thompson,Wallace,Wong
p. 4477 - 4480
(2007/10/03)

3-aryloxy-3-substituted propanamines
The present invention provides 3-aryloxy-3-substituted propanamines capable of inhibiting the uptake of serotonin and norepinephrine.
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(2008/06/13)

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Chemical Properties

Melting Point: 74-76°C
Boiling Point: 290.1±30.0 °C(Predicted)
Density: 1.111±0.06 g/cm3(Predicted)
Solubility:Chloroform (Slightly), Methanol (Slightly)
Storage Temp.:Room Temperature, under inert atmosphere
PKA: 14.35±0.20(Predicted)
PSA: 51.71000
LogP: 1.73320

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